Reactome | EEF1A2 [cytosol]

EEF1A2 [cytosol]

Stable Identifier

R-HSA-3907261

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Elongation factor 1-alpha 2, EF1A2_HUMAN

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External Reference Information

External Reference

UniProt:Q05639 EEF1A2

Gene Names

EEF1A2, EEF1AL, STN

Chain

initiator methionine:, chain:2-463

Reference Genes

BioGPS Gene:1917 EEF1A2

COSMIC (genes):EEF1A2 EEF1A2

CTD Gene:1917 EEF1A2

dbSNP Gene:1917 EEF1A2

ENSEMBL:ENSG00000101210 EEF1A2

ENSEMBL_homo_sapiens_GENE:ENSG00000101210.14 EEF1A2

HGNC:3192 EEF1A2

KEGG Gene (Homo sapiens):1917 EEF1A2

Monarch:1917 EEF1A2

NCBI Gene:1917 EEF1A2

OMIM:602959 EEF1A2

UCSC:Q05639 EEF1A2

Reference Transcript

RefSeq:NM_001958.3 EEF1A2

Other Identifiers

11744093_a_at

11744094_x_at

16921258

1917

204540_3p_at

204540_PM_at

204540_at

35174_i_at

35175_f_at

3913893

3913894

3913895

3913896

3913897

3913899

3913900

3913901

3913904

3913906

3913907

3913908

8067652

A_23_P256033

A_33_P3229953

GE59974

GO:0000166

GO:0003746

GO:0003824

GO:0003924

GO:0005515

GO:0005525

GO:0005737

GO:0005764

GO:0005773

GO:0005853

GO:0006412

GO:0006414

GO:0006629

GO:0006914

GO:0008135

GO:0012501

GO:0016787

GO:0019901

GO:0030163

GO:0043065

GO:0043226

GO:0045182

GO:0045202

GO:0090218

GO:0098574

GO:1904714

HMNXSV003006703

ILMN_2108735

PH_hs_0025294

TC20001032.hg

X70940_s_at

g4503474_3p_at

g4503474_3p_s_at

g4503474_3p_x_at

Participates

as a candidate of

EEF1A1-like proteins [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_001949.1

OpenTargets

ENSG00000101210

ZINC - Substances

EF1A2_HUMAN

ZINC target

Q05639

PRO

Q05639

PDB

8B6Z, 3C5J

GeneCards

Q05639

HPA

ENSG00000101210-EEF1A2

Ensembl

ENSG00000101210, ENST00000217182, ENSP00000217182

Pharos - Targets

Q05639

Orphanet

23526

ZINC - Predictions - Purchasable

EF1A2_HUMAN

HMDB Protein

HMDBP01879

Interactors (7)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P59595 N	9	N [cytosol] (R-COV-9683625) p-S177-N [cytosol] (R-COV-9683754) ADPr-p-S177-N [cytosol] (R-COV-9686058) SUMO1-K62-ADPr-p-S177-N [cytosol] (R-COV-9682916) SUMO1-K62-ADPr-p-S177-N [viral capsid] (R-COV-9685478) SUMO1-K62-ADPr-p-S177-N [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-COV-9683641) N [plasma membrane] (R-COV-9683611) SUMO1-K62-ADPr-p-S177-N [nucleolus] (R-COV-9683730) SUMO1-K62-ADPr-p-S177-N [plasma membrane] (R-COV-9686063)	0.691	10
UniProt:P10636-8 MAPT	3	p-S199,S202,S262,S396,S404,S409,T181,T231-MAPT-8 [cytosol] (R-HSA-9836400) p-S262,S356,S396-MAPT-8 [cytosol] (R-HSA-9619521) MAPT-8 [cytosol] (R-HSA-9619519)	0.569	8
UniProt:P26640 VARS1	1	VARS [cytosol] (R-HSA-379648)	0.564	2
UniProt:Q5S007 LRRK2	1	LRRK2 [cytosol] (R-HSA-5661173)	0.564	3
UniProt:P24534 EEF1B2	1	EEF1B2 [cytosol] (R-HSA-156926)	0.564	2
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.556	3
UniProt:Q15843 NEDD8	8	C111-AcM-UBE2M-G76-NEDD8 [nucleoplasm] (R-HSA-8952504) NEDD8 [nucleoplasm] (R-HSA-8955926) C116-AcM-UBE2F-G76-NEDD8 [cytosol] (R-HSA-8951739) NEDD8(77-81) [cytosol] (R-HSA-6782654) NEDD8(1-81) [cytosol] (R-HSA-5690794) C237-UBA3-G76-NEDD8 [cytosol] (R-HSA-8951647) NEDD8 [cytosol] (R-HSA-416969) C111-AcM-UBE2M-G76-NEDD8 [cytosol] (R-HSA-4419895)	0.527	2

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