CEBPB homodimerization

Stable Identifier
R-HSA-3857336
Type
Reaction [binding]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
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RSK1/2/3-mediated phosphorylation of CEBPB promotes the formation of CEBPB homodimers which are active as transcription factors (Lee, Miller et al. 2010; Lee, Shuman et al. 2010).
Literature References
PubMed ID Title Journal Year
20351173 RSK-mediated phosphorylation in the C/EBP{beta} leucine zipper regulates DNA binding, dimerization, and growth arrest activity

Shuman, JD, Cohen, MS, Sakchaisri, K, Taunton, J, Lee, S, Sebastian, T, Smart, RC, Veenstra, TD, Xiao, Z, Yu, LR, Miller, M, Copeland, TD, Guszczynski, T, Johnson, PF

Mol. Cell. Biol. 2010
20452968 CCAAT/Enhancer-binding protein beta DNA binding is auto-inhibited by multiple elements that also mediate association with p300/CREB-binding protein (CBP)

Shuman, JD, Miller, M, Johnson, PF, Lee, S

J. Biol. Chem. 2010
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