Cathepsin G proteolyzes IGF:IGFBP3:ALS

Stable Identifier
R-HSA-381500
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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Cathepsin G cleaves IGFBP-3 between amino acids 168 and 169 and between amino acids 226 and 227, releasing IGF from the IGF:IGFBP-3:ALS Complex.

Literature References
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
serine-type endopeptidase activity of Cathepsin G [plasma membrane]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed
Created