Reactome | CTCF [nucleoplasm]

CTCF [nucleoplasm]

Stable Identifier

R-HSA-3782562

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Transcriptional repressor CTCF, CTCF_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P49711 CTCF

Gene Names

CTCF

Chain

chain:1-727

Reference Genes

BioGPS Gene:10664 CTCF

COSMIC (genes):CTCF CTCF

CTD Gene:10664 CTCF

dbSNP Gene:10664 CTCF

ENSEMBL:ENSG00000102974 CTCF

ENSEMBL_homo_sapiens_GENE:ENSG00000102974.16 CTCF

HGNC:13723 CTCF

KEGG Gene (Homo sapiens):10664 CTCF

Monarch:10664 CTCF

NCBI Gene:10664 CTCF

OMIM:604167 CTCF

UCSC:P49711 CTCF

Reference Transcript

Other Identifiers

10664

11755514_s_at

16820193

202521_PM_at

202521_at

35319_at

3665604

3665607

3665608

3665612

3665613

3665616

3665617

3665618

3665620

3665621

3665623

3665624

3665625

3665630

3665631

3665633

3665634

3665635

7996593

A_14_P116120

A_14_P117085

A_24_P347704

A_24_P356254

GE59031

GO:0000122

GO:0000775

GO:0000793

GO:0000976

GO:0000978

GO:0001221

GO:0001227

GO:0001673

GO:0003677

GO:0003682

GO:0003700

GO:0005515

GO:0005634

GO:0005654

GO:0005694

GO:0005730

GO:0006306

GO:0006325

GO:0006351

GO:0006355

GO:0007059

GO:0008270

GO:0008285

GO:0010628

GO:0010629

GO:0040029

GO:0043035

GO:0043226

GO:0043565

GO:0044027

GO:0045892

GO:0045893

GO:0045944

GO:0046872

GO:0070602

GO:0071459

GO:0071514

GO:0140110

GO:0140588

HMNXSV003025160

ILMN_1786015

PH_hs_0024876

TC16000542.hg

U25435_at

g5729789_3p_at

Participates

as a component of

Cross References

RefSeq

NP_001177951.1, XP_016878357.1, NP_006556.1

OpenTargets

ENSG00000102974

GeneCards

P49711

HPA

ENSG00000102974-CTCF

Ensembl

ENST00000646076, ENST00000264010, ENSP00000493495, ENST00000401394, ENSG00000102974, ENSP00000494408, ENSP00000264010, ENSP00000494538, ENSP00000495348, ENST00000642819, ENSP00000384707, ENST00000645699, ENST00000644753

PRO

P49711

Pharos - Targets

P49711

Orphanet

22402

PDB

8SST, 5YEH, 5K5L, 5T00, 7W1M, 5YEG, 8SSS, 5UND, 5K5J, 5YEF, 2CT1, 5K5H, 8SSR, 5KKQ, 5K5I, 5T0U, 8SSQ, 5YEL, 6QNX, 8SSU, 1X6H

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q00341 HDLBP	1	HDLBP [plasma membrane] (R-HSA-8858026)	0.581	4
UniProt:P05067 APP	20	APP(18-770) [trans-Golgi network membrane] (R-HSA-5229136) APP-C99 [cytosol] (R-HSA-9617603) APP(18-770) [extracellular region] (R-HSA-49335) APP(18-770) [platelet alpha granule lumen] (R-HSA-139835) APP(18-687) [extracellular region] (R-HSA-9010033) APP(688-770) [plasma membrane] (R-HSA-9010028) APP(18-770) [Golgi lumen] (R-HSA-8871509) APP(18-770) [plasma membrane] (R-HSA-9010038) APP(18-671) [endosome lumen] (R-HSA-5693003) APP(714-770) [endosome lumen] (R-HSA-6783325) APP(712-770) [endosome lumen] (R-HSA-6783331) APP(672-770) [endosome lumen] (R-HSA-9010082) APP(672-713) [endosome lumen] (R-HSA-5692993) APP(672-711) [endosome lumen] (R-HSA-6783333) APP(18-770) [endosome lumen] (R-HSA-5229077) p-APP [endoplasmic reticulum lumen] (R-HSA-8957012) APP [endoplasmic reticulum lumen] (R-HSA-8956696) APP(672-711) [extracellular region] (R-HSA-976740) APP(672-711) [cytosol] (R-HSA-877188) APP(672-713) [extracellular region] (R-HSA-879340)	0.556	3
UniProt:Q12933 TRAF2	5	TRAF2 [nucleoplasm] (R-HSA-8862199) K63polyUb-TRAF2 [nucleoplasm] (R-HSA-8862194) K63polyUb-TRAF2 [cytosol] (R-HSA-8862193) PolyUb-TRAF2 [cytosol] (R-HSA-6782848) TRAF2 [cytosol] (R-HSA-66370)	0.556	3
UniProt:Q9UGL1 KDM5B	1	KDM5B [nucleoplasm] (R-HSA-3215031)	0.524	8
UniProt:Q9HCK8 CHD8	1	CHD8 [nucleoplasm] (R-HSA-3221598)	0.463	3

Cite Us!