Caspase-mediated cleavage of Etk

Stable Identifier
R-HSA-351849
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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Cleavage of Etk by caspase-3 stimulates its kinase activity. Overexpression of the fragment induces apoptosis (Wu et al.,2001).

Literature References
PubMed ID Title Journal Year
11278797 Proteolytic activation of ETK/Bmx tyrosine kinase by caspases

Wu, YM, Huang, CL, Kung, HJ, Huang, CY

J Biol Chem 2001
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
cysteine-type endopeptidase activity of Caspase-3 [cytosol]
Physical Entity
Activity
Orthologous Events
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Reviewed
Created