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KAT8 [nucleoplasm]
Stable Identifier
R-HSA-3321802
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Histone acetyltransferase KAT8, KAT8_HUMAN, MYST1, MOF
Locations in the PathwayBrowser
Expand all
Chromatin organization (Homo sapiens)
Chromatin modifying enzymes (Homo sapiens)
HATs acetylate histones (Homo sapiens)
MSL acetylates histone H4 (Homo sapiens)
MSL [nucleoplasm] (Homo sapiens)
KAT8 [nucleoplasm] (Homo sapiens)
NSL acetylates histone H4 (Homo sapiens)
NSL [nucleoplasm] (Homo sapiens)
KAT8 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9H7Z6 KAT8
Gene Names
KAT8, MOF, MYST1, PP7073
Chain
initiator methionine:1, chain:2-458
Reference Genes
BioGPS Gene:84148 KAT8
COSMIC (genes):KAT8 KAT8
CTD Gene:84148 KAT8
dbSNP Gene:84148 KAT8
ENSEMBL:ENSG00000103510 KAT8
HGNC:17933 KAT8
KEGG Gene (Homo sapiens):84148 KAT8
Monarch:84148 KAT8
NCBI Gene:84148 KAT8
OMIM:609912 KAT8
UCSC:Q9H7Z6 KAT8
Reference Transcript
RefSeq:NM_182958.2 KAT8
RefSeq:NM_032188.2 KAT8
Other Identifiers
0002450504
11720236_a_at
11732338_a_at
16818184
214885_at
221820_s_at
2GIV
2PQ8
2Y0M
35986_at
35987_g_at
35988_i_at
3656856
3656857
3656858
3656860
3656862
3656868
3656869
3656870
3656871
3656872
3656873
3656875
3656876
3656877
3656878
3656879
3656880
3656881
3656882
3QAH
3TOA
3TOB
4DNC
5H43
5J8C
5J8F
5WCI
66324
6BA2
6BA4
6CT2
7995055
84148
A_33_P3287745
AAF72665
AAH37773
AAL55762
AAL56648
AC009088
AC135050
AF217501
AF260665
AF289578
AK021872
AK024102
AK291106
AL050395
BAB13924
BAB14827
BAF83795
BC037773
CAH56416
CCDS10706
CCDS45468
CH471192
EAW52157
EAW52158
ENSG00000103510
ENSP00000219797
ENSP00000406037
ENSP00000456933
ENST00000219797
ENST00000219797.8
ENST00000448516
ENST00000448516.6
ENST00000543774
ENST00000543774.6
EntrezGene:84148
EntrezGene:KAT8
GE56306
GO:0000123
GO:0000228
GO:0000776
GO:0000790
GO:0002376
GO:0003674
GO:0004402
GO:0005515
GO:0005575
GO:0005622
GO:0005623
GO:0005634
GO:0005654
GO:0005694
GO:0006325
GO:0006355
GO:0006464
GO:0006914
GO:0008134
GO:0008150
GO:0009056
GO:0009058
GO:0010506
GO:0016363
GO:0016407
GO:0016573
GO:0016740
GO:0016746
GO:0019899
GO:0030099
GO:0030154
GO:0032991
GO:0034641
GO:0035064
GO:0042393
GO:0043167
GO:0043226
GO:0043981
GO:0043982
GO:0043984
GO:0043995
GO:0043996
GO:0045892
GO:0045893
GO:0045944
GO:0046872
GO:0046972
GO:0048856
GO:0051276
GO:0071339
GO:0072487
HGNC:17933
HPA066324
Hs.42343.0.S1_3p_a_at
Hs.42343.1.S1_3p_x_at
ILMN_1804679
IPR000953
IPR002717
IPR016181
IPR016197
IPR025995
IPR036388
IPR037906
IPR040706
KAT8
KAT8-201
KAT8-202
KAT8-206
MIM:609912
NM_032188
NM_182958
NP_115564
NP_892003
PF01853
PF11717
PF17772
PH_hs_0003107
SM00298
TC16000371.hg
UPI000004FA7B
UPI00001B02B6
XM_011545970
XM_011545971
XP_011544272
XP_011544273
Participant Of
hasComponent
MSL [nucleoplasm]
NSL [nucleoplasm]
Inferred To
KAT8 [nucleoplasm] (Bos taurus)
KAT8 [nucleoplasm] (Canis familiaris)
KAT8 [nucleoplasm] (Drosophila melanogaster)
KAT8 [nucleoplasm] (Gallus gallus)
KAT8 [nucleoplasm] (Mus musculus)
KAT8 [nucleoplasm] (Rattus norvegicus)
KAT8 [nucleoplasm] (Sus scrofa)
KAT8 [nucleoplasm] (Xenopus tropicalis)
Cross References
RefSeq
NP_115564.2
,
NP_892003.2
OpenTargets
ENSG00000103510
GeneCards
Q9H7Z6
ZINC target
Q9H7Z6
PRO
Q9H7Z6
PDB
3QAH
,
5J8C
,
6CT2
,
5J8F
,
5H43
,
2GIV
,
5WCI
,
3TOA
,
6BA2
,
2PQ8
,
6BA4
,
3TOB
,
4DNC
,
2Y0M
HMDB Protein
HMDBP09985
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P61964 WDR5
1
WDR5 [nucleoplasm]
(R-HSA-1629838)
0.597
4
UniProt:Q03164 KMT2A
1
KMT2A [nucleoplasm]
(R-HSA-1183223)
0.591
3
UniProt:P04637 TP53
27
TP53 [cytosol]
(R-HSA-8869337)
Unfolded TP53 [cytosol]
(R-HSA-6813797)
PolyUb-TP53 [nucleoplasm]
(R-HSA-6782509)
SUMO2,3-K386-TP53 [nucleoplasm]
(R-HSA-2997661)
Me2K-370,382-TP53 [nucleoplasm]
(R-HSA-3222242)
p-S15,S20,Me-R333,Me2-R335,R337-TP53 [nucleoplasm]
(R-HSA-6804378)
Me2-K373-TP53 [nucleoplasm]
(R-HSA-6805759)
Me1-K372,p-S15,S20-TP53 [nucleoplasm]
(R-HSA-6805719)
MeK-370,p-S15,S20-TP53 [nucleoplasm]
(R-HSA-3222226)
Me-K382,p-S15,S20-TP53 [nucleoplasm]
(R-HSA-3222124)
PolyUb,p-S15,S20-TP53 [nucleoplasm]
(R-HSA-6804446)
p-S15,S392-TP53 [nucleoplasm]
(R-HSA-3222015)
p-S315-TP53 [nucleoplasm]
(R-HSA-6805106)
p-S15,S20,S269,T284-TP53 [nucleoplasm]
(R-HSA-6805133)
p-S15,S33,S46-TP53 [nucleoplasm]
(R-HSA-6805268)
p-S15,S20,S392-TP53 [nucleoplasm]
(R-HSA-6805053)
p-T55-TP53 [nucleoplasm]
(R-HSA-6805400)
Ac-K120,p-S15,S20-TP53 [nucleoplasm]
(R-HSA-6805656)
Ac-K120,K382,p-S15,S20-TP53 [nucleoplasm]
(R-HSA-6805631)
Ac-K382,p-S15,S20-TP53 [nucleoplasm]
(R-HSA-5628868)
p-S37-TP53 [nucleoplasm]
(R-HSA-3239022)
p-S15,S20,S46-TP53 [nucleoplasm]
(R-HSA-6798369)
PolyUb-TP53 [nucleoplasm]
(R-HSA-6793679)
PolyUb-TP53 [cytosol]
(R-HSA-6793681)
p-S15,S20-TP53 [nucleoplasm]
(R-HSA-69683)
p-S15-TP53 [nucleoplasm]
(R-HSA-69507)
TP53 [nucleoplasm]
(R-HSA-69488)
0.564
2
UniProt:Q15291 RBBP5
1
RBBP5 [nucleoplasm]
(R-HSA-1629836)
0.462
2
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