Reactome | p-S407,Y641-STAT6 is dimerized

p-S407,Y641-STAT6 is dimerized

Stable Identifier

R-HSA-3249372

Type

Reaction [binding]

Species

Homo sapiens

Compartment

cytosol

ReviewStatus

5/5

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Phosphorylation of STAT6 results in the homodimerization and nucleus translocation of STAT6 where it binds to the target sites to initiate transcription.

Literature References

PubMed ID	Title	Journal	Year
22000020	Activation of STAT6 by STING is critical for antiviral innate immunity Yang, J, Qin, Z, Chen, H, Guan, Y, Zhou, X, Barber, G, Jiang, Z, Sun, H, Ishikawa, H, You, F, Sun, W, Gutman, D, Tang, H, Chen, L, Wang, Y, Gu, J, Xia, W	Cell	2011