SUMOylation of TFAP2B with SUMO1

Stable Identifier
R-HSA-3234084
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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UBE2I (UBC9) interacts with the C terminal region of TFAP2B (Eloranta and Hurst 2002). As inferred from TFAP2C, SUMOylation of TFAP2B occurs at lysine in the VKYE motif and. therefore UBC9 is assumed to catalyze the ligation of SUMO1 to TFAP2B.

Literature References
PubMed ID Title Journal Year
12072434 Transcription factor AP-2 interacts with the SUMO-conjugating enzyme UBC9 and is sumolated in vivo

Eloranta, JJ, Hurst, HC

J. Biol. Chem. 2002
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
SUMO transferase activity of SUMO1:C93-UBE2I [nucleoplasm]
Physical Entity
Activity
Inferred From
Authored
Reviewed
Created