AP-1 complex stimulates KDM6B transcription

Stable Identifier
R-HSA-3222546
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
Binding of the AP-1 (JUN:FOS) subunit JUN to the KDM6B (JMJD3) promoter, as well as the transcription of KDM6B gene increases after ERK activation (Lin et al. 2012).
Literature References
PubMed ID Title Journal Year
22020331 Loss of the candidate tumor suppressor BTG3 triggers acute cellular senescence via the ERK-JMJD3-p16(INK4a) signaling axis

Wang, CC, Lin, TY, Lin, WC, Yang, HC, Shieh, SY, Lai, PL, Cheng, YC

Oncogene 2012
Participants
Participates
This event is regulated
Authored
Reviewed
Created
Cite Us!