DAXX binds Ub-MDM2 and USP7

Stable Identifier
R-HSA-3222072
Type
Reaction [binding]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
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DAXX paired amphipathic helix domain 2 (PAH2) binds MDM2, while DAXX PAH1 domain and acid rich region simultaneously bind USP7 (HAUSP) (Tang et al. 2006), forming a tripartite complex.
Literature References
PubMed ID Title Journal Year
16845383 Critical role for Daxx in regulating Mdm2

Wang, W, Zhang, J, Degenhardt, YY, Tang, J, Qu, LK, Michaelson, JS, Yang, X, El-Deiry, WS

Nat. Cell Biol. 2006
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