MRE11:dsDNA [cytosol]

Stable Identifier
R-HSA-3204308
Type
Complex
Species
Homo sapiens
Compartment
cytosol
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Literature References
PubMed ID Title Journal Year
23388631 DNA damage sensor MRE11 recognizes cytosolic double-stranded DNA and induces type I interferon by regulating STING trafficking

Kawai, T, Ishii, KJ, Akira, S, Kobayashi, J, Barber, GN, Saitoh, T, Kondo, T, Komatsu, K, Maruyama, K

Proc. Natl. Acad. Sci. U.S.A. 2013
Participants
components
Participates
as an output of
This entity regulates
Positively
Inferred To
MRE11:dsDNA [cytosol] (Bos taurus)
MRE11:dsDNA [cytosol] (Caenorhabditis elegans)
MRE11:dsDNA [cytosol] (Canis familiaris)
MRE11:dsDNA [cytosol] (Dictyostelium discoideum)
MRE11:dsDNA [cytosol] (Drosophila melanogaster)
MRE11:dsDNA [cytosol] (Gallus gallus)
MRE11:dsDNA [cytosol] (Mus musculus)
MRE11:dsDNA [cytosol] (Plasmodium falciparum)
MRE11:dsDNA [cytosol] (Rattus norvegicus)
MRE11:dsDNA [cytosol] (Saccharomyces cerevisiae)
MRE11:dsDNA [cytosol] (Schizosaccharomyces pombe)
MRE11:dsDNA [cytosol] (Sus scrofa)
MRE11:dsDNA [cytosol] (Xenopus tropicalis)
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