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PLXNB1 [plasma membrane]
Stable Identifier
R-HSA-3008951
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Plexin-B1, PLXB1_HUMAN
Icon
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
Axon guidance (Homo sapiens)
Semaphorin interactions (Homo sapiens)
Sema4D in semaphorin signaling (Homo sapiens)
Sema4D induced cell migration and growth-cone collapse (Homo sapiens)
SEMA4D interacts with Plexin-B1:ErbB2 (Homo sapiens)
Plexin-B1:ErbB2 [plasma membrane] (Homo sapiens)
PLXNB1 [plasma membrane] (Homo sapiens)
Sema4D mediated inhibition of cell attachment and migration (Homo sapiens)
Inactivation of R-Ras by Sema4D-Plexin-B1 GAP activity (Homo sapiens)
PLXNB1 [plasma membrane] (Homo sapiens)
SEMA4D interacts with Plexin-B1:Met (Homo sapiens)
Plexin-B1:Met [plasma membrane] (Homo sapiens)
PLXNB1 [plasma membrane] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (12/13) signalling events (Homo sapiens)
LARG binds plexin B1 (Homo sapiens)
G-protein alpha (12/13):LARG:Plexin B1 [plasma membrane] (Homo sapiens)
PLXNB1 [plasma membrane] (Homo sapiens)
PLXNB1 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:O43157 PLXNB1
Gene Names
PLXNB1, KIAA0407, PLXN5, SEP
Chain
signal peptide:1-19, chain:20-2135
Reference Genes
BioGPS Gene:5364 PLXNB1
COSMIC (genes):PLXNB1 PLXNB1
CTD Gene:5364 PLXNB1
dbSNP Gene:5364 PLXNB1
ENSEMBL:ENSG00000164050 PLXNB1
HGNC:9103 PLXNB1
KEGG Gene (Homo sapiens):5364 PLXNB1
Monarch:5364 PLXNB1
NCBI Gene:5364 PLXNB1
OMIM:601053 PLXNB1
UCSC:O43157 PLXNB1
Reference Transcript
RefSeq:NM_002673.5 PLXNB1
RefSeq:XM_017006631.1 PLXNB1
RefSeq:NM_001130082.2 PLXNB1
Other Identifiers
0004540053
11749426_a_at
11754713_a_at
16953329
215668_s_at
215807_s_at
2673184
2673185
2673186
2673188
2673191
2673192
2673194
2673197
2673198
2673200
2673201
2673203
2673205
2673206
2673207
2673208
2673209
2673210
2673211
2673212
2673213
2673214
2673215
2673216
2673217
2673220
2673221
2673222
2673224
2673225
2673226
2673227
2673228
2673229
2673230
2673231
2673232
2673233
2673234
2673235
2673236
2673237
2673238
2673239
2673240
2673241
2673243
2673244
2673245
2673246
2673248
2673249
2673250
2673251
2673252
2673253
2673255
2673256
2JPH
2OS6
2R2O
2REX
33783_at
3HM6
3OL2
3SU8
3SUA
40586
5364
5B4W
8086908
A_23_P57961
AAI46794
AB007867
AJ011414
AJ011415
BAA23703
BC146793
CAB56221
CAB56222
CAB57277
CCDS2765
CH471055
EAW64865
ENSG00000164050
ENSP00000296440
ENSP00000351338
ENSP00000395987
ENSP00000414199
ENST00000296440
ENST00000296440.10
ENST00000358536
ENST00000358536.8
ENST00000449094
ENST00000449094.5
ENST00000456774
ENST00000456774.5
EntrezGene:5364
EntrezGene:PLXNB1
GE81179
GO:0000902
GO:0002116
GO:0003674
GO:0004888
GO:0005096
GO:0005515
GO:0005575
GO:0005576
GO:0005623
GO:0005886
GO:0005887
GO:0007010
GO:0007155
GO:0007162
GO:0007165
GO:0007186
GO:0008150
GO:0008283
GO:0008360
GO:0014068
GO:0016020
GO:0016021
GO:0016477
GO:0017154
GO:0021700
GO:0022607
GO:0030154
GO:0030215
GO:0030234
GO:0030334
GO:0032794
GO:0032991
GO:0033689
GO:0035556
GO:0038023
GO:0040011
GO:0043087
GO:0043547
GO:0043931
GO:0048812
GO:0048856
GO:0048870
GO:0050772
GO:0051493
GO:0071526
GO:1900220
GO:1902287
GO:1904862
HGNC:9103
HPA040586
Hs.278311.1.S1_3p_a_at
Hs.312939.0.S1_3p_s_at
ILMN_1742330
IPR001627
IPR002165
IPR002909
IPR008936
IPR013548
IPR013783
IPR014756
IPR015943
IPR016201
IPR031148
IPR036352
IPR041019
IPR041362
MIM:601053
NM_001130082
NM_002673
NP_001123554
NP_002664
PF01403
PF01437
PF01833
PF08337
PF17960
PF18020
PH_hs_0014265
PLXNB1
PLXNB1-201
PLXNB1-202
PLXNB1-203
PLXNB1-204
SM00423
SM00429
SM00630
TC03001378.hg
UPI0000038131
UPI0000038132
UPI00000727F2
X87904
X87904_at
XM_011533833
XM_011533834
XM_011533835
XM_011533836
XM_011533837
XM_017006630
XM_017006631
XM_024453600
XP_011532135
XP_011532136
XP_011532137
XP_011532138
XP_011532139
XP_016862119
XP_016862120
XP_024309368
XR_001740177
XR_940457
XR_940458
Participant Of
hasComponent
G-protein alpha (12/13):LARG:Plexin B1 [plasma membrane]
Plexin-B1:ErbB2 [plasma membrane]
Plexin-B1:Met [plasma membrane]
input
LARG binds plexin B1
Other forms of this molecule
p-Y-PLXNB1 [plasma membrane]
Inferred To
PLXNB1 [plasma membrane] (Bos taurus)
PLXNB1 [plasma membrane] (Caenorhabditis elegans)
PLXNB1 [plasma membrane] (Canis familiaris)
PLXNB1 [plasma membrane] (Danio rerio)
PLXNB1 [plasma membrane] (Drosophila melanogaster)
PLXNB1 [plasma membrane] (Gallus gallus)
PLXNB1 [plasma membrane] (Mus musculus)
PLXNB1 [plasma membrane] (Rattus norvegicus)
PLXNB1 [plasma membrane] (Sus scrofa)
PLXNB1 [plasma membrane] (Xenopus tropicalis)
Homologues of PLXNB1 [plasma membrane] (Caenorhabditis elegans)
Homologues of PLXNB1 [plasma membrane] (Drosophila melanogaster)
Cross References
RefSeq
NP_002664.2
,
XP_016862120.1
,
NP_001123554.1
OpenTargets
ENSG00000164050
GeneCards
O43157
PRO
O43157
PDB
2REX
,
3HM6
,
2OS6
,
5B4W
,
2R2O
,
2JPH
,
3SU8
,
3OL2
,
3SUA
Interactors (5)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q92730 RND1
1
RND1 [cytosol]
(R-HSA-396949)
0.775
5
UniProt:P08581 MET
7
p-Y1349,Y1356-MET [plasma membrane]
(R-HSA-6807032)
p-Y1234,Y1235,Y1356-MET [plasma membrane]
(R-HSA-6807014)
MonoUb-K,p-Y1234,Y1235,Y1349,Y1356-MET [plasma membrane]
(R-HSA-8875181)
MonoUb-K,p-Y1003,4Y-MET [plasma membrane]
(R-HSA-8875180)
p-Y1003,4Y-MET [plasma membrane]
(R-HSA-8874689)
MET [plasma membrane]
(R-HSA-419603)
p-Y1234,Y1235,Y1349,Y1356-MET [plasma membrane]
(R-HSA-6806973)
0.775
9
UniProt:P61587 RND3
0.676
3
UniProt:P52198 RND2
0.558
2
UniProt:Q04912 MST1R
3
MST1R (25-304) [plasma membrane]
(R-HSA-6800303)
p-Y1238,1239,1353,1360-MST1R (310-1400) [plasma membrane]
(R-HSA-8852533)
MST1R (310-1400) [plasma membrane]
(R-HSA-6800308)
0.524
3
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