Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Contributors
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Contributors
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
VRK2-2 [cytosol]
Stable Identifier
R-HSA-2995378
Type
Genes and Transcripts [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
VRK2B
Locations in the PathwayBrowser
Expand all
Cell Cycle (Homo sapiens)
Cell Cycle, Mitotic (Homo sapiens)
M Phase (Homo sapiens)
Mitotic Metaphase and Anaphase (Homo sapiens)
Mitotic Anaphase (Homo sapiens)
Nuclear Envelope (NE) Reassembly (Homo sapiens)
Initiation of Nuclear Envelope (NE) Reformation (Homo sapiens)
ANKLE2 binds VRK1,(VRK2) (Homo sapiens)
ANKLE2:VRK1/VRK2 [endoplasmic reticulum membrane] (Homo sapiens)
VRK1,(VRK2) [cytosol] (Homo sapiens)
VRK2-2 [cytosol] (Homo sapiens)
VRK1,(VRK2) [cytosol] (Homo sapiens)
VRK2-2 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q86Y07-2 VRK2
Gene Names
VRK2
Other Identifiers
11742755_a_at
16880304
205126_PM_at
205126_at
2483452
2483453
2483458
2483459
2483460
2483462
2483463
2483465
2483466
2483479
2483481
2483483
2483484
2483485
2483489
2483491
2483498
2483500
2483501
2483503
2483504
2483508
2483509
2483510
33124_at
7444
8042086
AB000450_at
A_14_P107251
A_14_P120903
A_23_P119992
A_33_P3417990
GE53013
GO:0000166
GO:0003824
GO:0004672
GO:0004674
GO:0005515
GO:0005524
GO:0005634
GO:0005635
GO:0005737
GO:0005739
GO:0005783
GO:0005789
GO:0006468
GO:0007165
GO:0016020
GO:0016301
GO:0016310
GO:0016740
GO:0019901
GO:0019904
GO:0023052
GO:0031966
GO:0032991
GO:0034599
GO:0036211
GO:0043226
GO:0043408
GO:0046777
GO:0106310
GO:0140096
GO:2000659
HMNXSV003003736
HMNXSV003005102
HMNXSV003020600
ILMN_1750088
PH_hs_0004736
TC02000331.hg
TC02003252.hg
g5454163_3p_at
Participates
as a candidate of
VRK1,(VRK2) [cytosol] (Homo sapiens)
Other forms of this molecule
VRK2-2 [nucleoplasm]
Inferred To
VRK2 [cytosol]
(Bos taurus)
VRK2 [cytosol]
(Canis familiaris)
VRK2-2 [cytosol]
(Caenorhabditis elegans)
VRK2-2 [cytosol]
(Drosophila melanogaster)
VRK2-2 [cytosol]
(Gallus gallus)
VRK2-2 [cytosol]
(Mus musculus)
VRK2-2 [cytosol]
(Sus scrofa)
Vrk2 [cytosol]
(Rattus norvegicus)
Cross References
RefSeq
NP_001123953.1
,
NP_001275767.1
,
XP_006712155.1
,
XP_016860349.1
,
XP_016860350.1
,
NP_001123954.1
,
XP_006712153.1
,
NP_006287.2
,
XP_016860347.1
,
NP_001123955.1
,
XP_016860351.1
,
XP_005264597.1
,
NP_001123952.1
,
XP_006712156.1
,
NP_001275766.1
,
XP_016860348.1
,
XP_011531394.1
,
NP_001275765.1
,
NP_001275768.1
,
XP_016860352.1
,
XP_006712154.1
ZINC - World Drugs
VRK2_HUMAN
Guide to Pharmacology - Targets
2276
OpenTargets
ENSG00000028116
ZINC - FDA approved
VRK2_HUMAN
ZINC - Substances
VRK2_HUMAN
ZINC target
Q86Y07
PRO
Q86Y07
PDB
5UU1
,
2V62
,
8Q1Z
,
6NCG
ZINC - Investigational
VRK2_HUMAN
IntEnz
2.7.11.1
GeneCards
Q86Y07
HPA
ENSG00000028116-VRK2
Ensembl
ENST00000648897
,
ENSP00000408002
,
ENST00000440705
,
ENSP00000402375
,
ENSP00000398323
,
ENSP00000404156
,
ENST00000435505
,
ENSG00000028116
,
ENST00000417641
,
ENST00000340157
,
ENST00000412104
,
ENSP00000497378
,
ENSP00000342381
Pharos - Targets
Q86Y07
ZINC - Predictions - Purchasable
VRK2_HUMAN
HMDB Protein
HMDBP01323
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q8N4V1 MMGT1
1
MMGT1 [Golgi membrane]
(R-HSA-5216137)
0.556
3
UniProt:Q02750 MAP2K1
20
MAP2K1(9-393) [cytosol]
(R-HSA-5211353)
MAP2K1(2-8) [cytosol]
(R-HSA-5211342)
MAP2K1 F53S [cytosol]
(R-HSA-9652034)
MAP2K1 D67N [cytosol]
(R-HSA-9652016)
MAP2K1 Q56P [cytosol]
(R-HSA-9652064)
MAP2K1 E203K [cytosol]
(R-HSA-9652023)
MAP2K1 V60E [cytosol]
(R-HSA-9652067)
MAP2K1 P124S [cytosol]
(R-HSA-9652062)
MAP2K1 Y130C [cytosol]
(R-HSA-9652101)
MAP2K1 C121S [cytosol]
(R-HSA-9652013)
MAP2K1 G128V [cytosol]
(R-HSA-9652047)
MAP2K1 F53L [cytosol]
(R-HSA-9652031)
MAP2K1 K57N [cytosol]
(R-HSA-9652050)
MAP2K1 K57T [cytosol]
(R-HSA-9652052)
MAP2K1 F53V [cytosol]
(R-HSA-9652038)
MAP2K1 D67Y [cytosol]
(R-HSA-9652019)
MAP2K1 G128D [cytosol]
(R-HSA-9652043)
MAP2K1 P124L [cytosol]
(R-HSA-9652056)
MAP2K1 F53Y [cytosol]
(R-HSA-9652041)
MAP2K1 L42_K57del [cytosol]
(R-HSA-9652026)
0.524
2
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text