Reactome | ERO1L [endoplasmic reticulum lumen]

ERO1L [endoplasmic reticulum lumen]

Stable Identifier

R-HSA-265076

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum lumen

Synonyms

Ero1-like alpha

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q96HE7 ERO1A

Gene Names

ERO1A, ERO1L, UNQ434/PRO865

Chain

signal peptide:1-23, chain:24-468

Reference Genes

BioGPS Gene:30001 ERO1A

COSMIC (genes):ERO1A ERO1A

CTD Gene:30001 ERO1A

dbSNP Gene:30001 ERO1A

ENSEMBL:ENSG00000197930 ERO1A

ENSEMBL_homo_sapiens_GENE:ENSG00000197930.13 ERO1A

HGNC:13280 ERO1A

KEGG Gene (Homo sapiens):30001 ERO1A

Monarch:30001 ERO1A

NCBI Gene:30001 ERO1A

OMIM:615435 ERO1A

UCSC:Q96HE7 ERO1A

Reference Transcript

RefSeq:NM_014584.2 ERO1A

Other Identifiers

11726320_at

11726321_a_at

16793024

218498_PM_s_at

218498_s_at

222646_PM_s_at

222646_s_at

225750_PM_at

225750_at

30001

3564794

3564795

3564796

3564797

3564798

3564799

3564800

3564801

3564803

3564805

3564806

3564811

3564812

3564815

3564817

3564820

3564822

3564826

3564827

3564830

3564832

3564833

3564834

3564841

3564842

44104_at

51096_at

59682_s_at

62599_r_at

65120_at

7979179

A_23_P106145

A_24_P407311

A_32_P387905

GE54725

GE87238

GO:0003824

GO:0005515

GO:0005576

GO:0005615

GO:0005783

GO:0005788

GO:0005789

GO:0005794

GO:0005796

GO:0006457

GO:0006915

GO:0006979

GO:0009266

GO:0012501

GO:0015035

GO:0016020

GO:0016491

GO:0016972

GO:0022417

GO:0023052

GO:0030154

GO:0030198

GO:0030425

GO:0030968

GO:0034975

GO:0034976

GO:0036211

GO:0042995

GO:0043226

GO:0043231

GO:0045454

GO:0050873

GO:0051085

GO:0051209

GO:0051604

GO:0055065

GO:0055085

GO:0070059

GO:0071456

GO:0071949

GO:0140096

HMNXSV003021850

HMNXSV003030169

Hs.10949.0.S1_3p_at

Hs.25740.0.S1_3p_a_at

ILMN_1744963

PH_hs_0027571

TC14001141.hg

g7657068_3p_a_at

Participates

as a component of

ERO1L:GPX7,8 [endoplasmic reticulum lumen] (Homo sapiens)

Inferred To

Homologues of ERO1L [endoplasmic reticulum lumen] (Sus scrofa)

ERO1A [endoplasmic reticulum lumen] (Canis familiaris)

ERO1L [endoplasmic reticulum lumen] (Bos taurus)

ERO1L [endoplasmic reticulum lumen] (Danio rerio)

ERO1L [endoplasmic reticulum lumen] (Gallus gallus)

ERO1L [endoplasmic reticulum lumen] (Mus musculus)

ERO1L [endoplasmic reticulum lumen] (Plasmodium falciparum)

ERO1L [endoplasmic reticulum lumen] (Rattus norvegicus)

ERO1L [endoplasmic reticulum lumen] (Sus scrofa)

ERO1L [endoplasmic reticulum lumen] (Xenopus tropicalis)

Cross References

RefSeq

NP_055399.1

OpenTargets

ENSG00000197930

HPA

ENSG00000197930-ERO1A

ZINC - Substances

ERO1A_HUMAN

GeneCards

Q96HE7

ZINC target

Q96HE7

Ensembl

ENSP00000379042, ENSG00000197930, ENST00000395686

PRO

Q96HE7

Pharos - Targets

Q96HE7

ZINC - Predictions - Purchasable

ERO1A_HUMAN

PDB

3AHQ, 3AHR

HMDB Protein

HMDBP08269

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P30101 PDIA3	3	PDIA3 [phagocytic vesicle] (R-HSA-1236870) PDIA3 [recycling endosome membrane] (R-HSA-8863849) PDIA3 [endoplasmic reticulum lumen] (R-HSA-901028)	0.667	3
UniProt:P07237 P4HB	3	P4HB [endoplasmic reticulum lumen] (R-HSA-174692) p-P4HB [endoplasmic reticulum lumen] (R-HSA-8956902) HC53,56-P4HB [endoplasmic reticulum lumen] (R-HSA-3341287)	0.656	3
UniProt:P02452 COL1A1	20	3x4Hyp-3Hyp-GlcGalHyl-COL1A1(23-1464) [endoplasmic reticulum lumen] (R-HSA-2023648) 3x4Hyp-GlcGalHyl-COL1A1(23-1464) [endoplasmic reticulum lumen] (R-HSA-2023667) GlcGalHyl-COL1A1(23-1464) [endoplasmic reticulum lumen] (R-HSA-2023604) GalHyl-COL1A1(23-1464) [endoplasmic reticulum lumen] (R-HSA-2022999) 3x4Hyp-3Hyp-GalHyl-COL1A1(23-1464) [endoplasmic reticulum lumen] (R-HSA-2023559) 3x4Hyp-GalHyl-COL1A1(23-1464) [endoplasmic reticulum lumen] (R-HSA-2023582) COL1A1(23-1464) [endoplasmic reticulum lumen] (R-HSA-1650777) 3x4Hyp-COL1A1(23-1464) [endoplasmic reticulum lumen] (R-HSA-1985659) 3x4Hyp-3Hyp-COL1A1(23-1464) [endoplasmic reticulum lumen] (R-HSA-2022446) 3x4Hyp-5Hyl-COL1A1(23-1464) [endoplasmic reticulum lumen] (R-HSA-2022951) 3x4Hyp-3Hyp-5Hyl-COL1A1(23-1464) [endoplasmic reticulum lumen] (R-HSA-2022954) 5Hyl-COL1A1(23-1464) [endoplasmic reticulum lumen] (R-HSA-1985663) Lysyl-pyrrolyl 5-hydroxylysyl collagen alpha-1(I) chain [extracellular region] (R-HSA-2396137) Lysyl-pyrrolyl 3,4-Hyp 5-Hyl collagen alpha-1(I) chain [extracellular region] (R-HSA-2396440) Lysyl-pyrrolyl 4-Hyp 5-Hyl collagen alpha-1(I) chain [extracellular region] (R-HSA-2396471) Lysyl-pyridinolyl 5-hydroxylysyl collagen alpha-1(I) chain [extracellular region] (R-HSA-2396464) Lysyl-pyridinolyl 4-Hyp 5-Hyl collagen alpha-1(I) chain [extracellular region] (R-HSA-2396068) Lysyl-pyridinolyl 3,4-Hyp 5-Hyl collagen alpha-1(I) chain [extracellular region] (R-HSA-2396388) Dehydrolysinonorlysyl 4-hydroxyprolyl collagen alpha-1(I) chain [extracellular region] (R-HSA-2396315) Dehydrolysinonorlysyl 4-Hyp 5-Gal-Hyl collagen alpha-1(I) chain [extracellular region] (R-HSA-2396441)	0.558	3
UniProt:P0DTC3 3a	9	O-glycosyl 3a [virion membrane] (R-COV-9694395) O-glycosyl 3a [endocytic vesicle membrane] (R-COV-9694729) O-glycosyl 3a [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-COV-9694386) GalNAc-O-3a [endoplasmic reticulum-Golgi intermediate compartment] (R-COV-9694658) 3a [endoplasmic reticulum-Golgi intermediate compartment] (R-COV-9694716) 3a [endoplasmic reticulum lumen] (R-COV-9694584) O-glycosyl 3a [endolysosome membrane] (R-COV-9754541) O-glycosyl 3a [plasma membrane] (R-COV-9694433) O-glycosyl 3a [extracellular region] (R-COV-9694387)	0.547	2
UniProt:Q9UH73 EBF1	1	EBF1 [nucleoplasm] (R-HSA-158571)	0.488	2

Cite Us!