Laminins:Nidogens binds collagen type IV networks

Stable Identifier
R-HSA-2426450
Type
Reaction [binding]
Species
Homo sapiens
Compartment
extracellular region
ReviewStatus
5/5
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Laminins:Nidogens binds collagen type IV networks
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Laminin-bound nidogens can bind to type IV collagen (Aumailey et al. 1989, 1993, Fox et al. 1991, Reinhardt et al. 1993, Ries et al. 2001, Bechtel et al. 2012).

Basement membrane formation involves self-assembly of laminin and of collagen IV into two independent networks (Yurchenco & Schittny 1990, Timpl & Brown 1996) that are connected by nidogen (Fox et al. 1991, Aumailley & Smyth 1998, Aumailey et al. 2000) and the heparan sulfate chains of both perlecan and agrin (Hohenester & Yurchenko 2013).
Literature References
PubMed ID Title Journal Year
3997977 Binding of laminin to type IV collagen: a morphological study

Yurchenco, PD, Tsilibary, EC, Furthmayr, H, Charonis, AS

J Cell Biol 1985
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Orthologous Events
Laminins:Nidogens binds collagen type IV networks (Bos taurus)
Laminins:Nidogens binds collagen type IV networks (Canis familiaris)
Laminins:Nidogens binds collagen type IV networks (Mus musculus)
Laminins:Nidogens binds collagen type IV networks (Rattus norvegicus)
Laminins:Nidogens binds collagen type IV networks (Sus scrofa)
Authored
Jupe, S  (2012-08-08)
Reviewed
Humphries, MJ  (2008-05-07)
Yamada, KM  (2008-05-07)
Hynes, R  (2008-05-07)
Ricard-Blum, S  (2013-08-13)
Created
Jupe, S  (2012-08-03)
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