Reactome | EPHX2 [cytosol]

EPHX2 [cytosol]

Stable Identifier

R-HSA-2142819

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Epoxide hydrolase 2, HYES_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P34913 EPHX2

Gene Names

EPHX2

Chain

chain:1-555

Reference Genes

BioGPS Gene:2053 EPHX2

COSMIC (genes):EPHX2 EPHX2

CTD Gene:2053 EPHX2

dbSNP Gene:2053 EPHX2

ENSEMBL:ENSG00000120915 EPHX2

ENSEMBL_homo_sapiens_GENE:ENSG00000120915.14 EPHX2

HGNC:3402 EPHX2

KEGG Gene (Homo sapiens):2053 EPHX2

Monarch:2053 EPHX2

NCBI Gene:2053 EPHX2

OMIM:132811 EPHX2

UCSC:P34913 EPHX2

Reference Transcript

Other Identifiers

11750932_a_at

11754640_a_at

17067284

2053

209368_PM_at

209368_at

3091404

3091405

3091408

3091409

3091410

3091411

3091412

3091414

3091418

3091422

3091424

3091425

3091426

3091427

3091429

3091431

3091433

3091435

3091436

3091437

3091439

3091441

3091442

3091443

3091444

3091445

41473_at

8145532

A_14_P107662

A_23_P8834

GE57562

GO:0000287

GO:0003824

GO:0004301

GO:0005576

GO:0005615

GO:0005737

GO:0005777

GO:0005782

GO:0005829

GO:0006629

GO:0008152

GO:0009636

GO:0010628

GO:0015643

GO:0016311

GO:0016787

GO:0016791

GO:0019439

GO:0033885

GO:0042577

GO:0042632

GO:0042803

GO:0043226

GO:0046272

GO:0046839

GO:0046872

GO:0052642

GO:0070062

GO:0090181

GO:0097176

HMNXSV003034918

ILMN_1709237

L05779_at

PH_hs_0032192

TC08000208.hg

g10197683_3p_at

Participates

as a member of

Cargo proteins containing PTS1 [cytosol] (Homo sapiens)

as a component of

EPHX2 dimer [cytosol] (Homo sapiens)

Other forms of this molecule

EPHX2 [peroxisomal matrix]

Inferred To

ephx2 [cytosol] (Xenopus tropicalis)

EPHX2 [cytosol] (Bos taurus)

EPHX2 [cytosol] (Canis familiaris)

EPHX2 [cytosol] (Dictyostelium discoideum)

EPHX2 [cytosol] (Gallus gallus)

EPHX2 [cytosol] (Mus musculus)

EPHX2 [cytosol] (Plasmodium falciparum)

EPHX2 [cytosol] (Rattus norvegicus)

EPHX2 [cytosol] (Sus scrofa)

Homologues of EPHX2 [cytosol] (Sus scrofa)

cb523 [cytosol] (Danio rerio)

Cross References

RefSeq

NP_001243411.1, NP_001243413.1, NP_001970.2, NP_001243412.1

ZINC - World Drugs

HYES_HUMAN

Guide to Pharmacology - Targets

2970

OpenTargets

ENSG00000120915

ZINC - FDA approved

HYES_HUMAN

ZINC - Substances

HYES_HUMAN

ZINC - Biogenic

HYES_HUMAN

ZINC target

P34913

PRO

P34913

PDB

4Y2Q, 3WKE, 3WKB, 5ALI, 5AM5, 5ALK, 3OTQ, 3I28, 3WK7, 5ALJ, 5AKZ, 5AIB, 5AK3, 1ZD3, 4JNC, 5ALE, 5AKI, 5ALR, 4OD0, 4OCZ, 5ALN, 4Y2U, 5AKL, 3KOO, 1S8O, 3WKA, 5AKK, 5AM3, 5ALF, 6I5E, 3WKD, 3ANS, 5ALW, 6AUM, 5AI0, 5AIA, 3WK6, 4Y2X, 4Y2R, 5AI5, 4C4X, 3I1Y, 5ALX, 1ZD2, 3PDC, 5ALS, 7EBA, 5FP0, 5ALZ, 5AIC, 4C4Z, 1ZD5, 5AK6, 5ALM, 5ALT, 5AI8, 4Y2P, 5AKY, 4HAI, 3WKC, 5ALO, 5ALH, 5AKX, 5AM0, 5AKG, 5AKH, 3WK8, 5AM2, 4J03, 5AK4, 5AI6, 5ALD, 3WK9, 4Y2T, 5AK5, 5AM4, 5ALG, 4Y2J, 4Y2V, 3WK5, 5ALP, 3ANT, 4Y2Y, 5AKE, 1VJ5, 5ALV, 5AHX, 5MWA, 5ALY, 5AI4, 5ALQ, 4Y2S, 5ALL, 5AM1, 4C4Y, 4X6X, 5AKJ, 6I5G, 5ALU, 5AI9, 1ZD4, 3WK4, 4X6Y

ZINC - Metabolites

HYES_HUMAN

IntEnz

3.1.3.76

GeneCards

P34913

HPA

ENSG00000120915-EPHX2

Ensembl

ENSG00000120915, ENST00000380476, ENSP00000369843, ENST00000521780, ENST00000521400, ENSP00000430302, ENSP00000430269

Pharos - Targets

P34913

Orphanet

28112

ZINC - Predictions - Purchasable

HYES_HUMAN

HMDB Protein

HMDBP01790