Reactome | Tranport of L-Glutamate (mitochondrial matrix) to cytosol

Tranport of L-Glutamate (mitochondrial matrix) to cytosol

Stable Identifier

R-HSA-212658

Type

Reaction [omitted]

Species

Homo sapiens

Compartment

mitochondrial matrix, cytosol

ReviewStatus

5/5

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Tranport of L-Glutamate (mitochondrial matrix) to cytosol

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Glutamate from the mitochondrial matrix is transported back into the cytosol, to be loaded into synaptic vesicles. Solute carrier 25 is a mitochondrial glutamate transporter known to transport glutamate, but it is unclear if this protein is involved in the transport of glutamate in neurons (Iioka et al. 1995).

Literature References

PubMed ID	Title	Journal	Year
2563364	Mechanism of L-glutamate transport in membrane vesicles from Bacillus stearothermophilus van Iwaarden, PR, de Vrij, W, Konings, WN, Bulthuis, RA	J. Bacteriol.	1989
3973444	[Studies on L-glutamate transport mechanism in human placental trophoblast microvilli membrane vesicles] Amasaki, M, Iioka, H, Moriyama, I, Ito, K, Ichijo, M, Kyuma, M	Nippon Sanka Fujinka Gakkai Zasshi	1985