Phosphorylated FOXO1A is excluded from the nucleus

Stable Identifier
R-HSA-211178
Type
Reaction [transition]
Species
Homo sapiens
Compartment
nucleoplasm, cytosol
ReviewStatus
5/5
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Phosphorylated FOXO1A is excluded from the nucleus
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Phosphorylated FOXO1A is transported from the nucleoplasm to the cytosol (Zhang et al. 2002).
Literature References
PubMed ID Title Journal Year
12228231 Phosphorylation of serine 256 suppresses transactivation by FKHR (FOXO1) by multiple mechanisms. Direct and indirect effects on nuclear/cytoplasmic shuttling and DNA binding

Unterman, TG, Gan, L, Pan, H, Zhang, X, Adam, S, Guo, S, Mesecar, A, Olson, ST, He, X

J Biol Chem 2002
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Orthologous Events
Phosphorylated FOXO1A is excluded from the nucleus (Bos taurus)
Phosphorylated FOXO1A is excluded from the nucleus (Caenorhabditis elegans)
Phosphorylated FOXO1A is excluded from the nucleus (Canis familiaris)
Phosphorylated FOXO1A is excluded from the nucleus (Danio rerio)
Phosphorylated FOXO1A is excluded from the nucleus (Drosophila melanogaster)
Phosphorylated FOXO1A is excluded from the nucleus (Gallus gallus)
Phosphorylated FOXO1A is excluded from the nucleus (Mus musculus)
Phosphorylated FOXO1A is excluded from the nucleus (Rattus norvegicus)
Phosphorylated FOXO1A is excluded from the nucleus (Sus scrofa)
Phosphorylated FOXO1A is excluded from the nucleus (Xenopus tropicalis)
Authored
Tello-Ruiz, MK  (2008-05-24)
Ferrer, J  (2008-05-24)
Reviewed
Jensen, J  (2008-05-13)
Created
D'Eustachio, P  (2008-01-29)
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