NEUROG3-dependent synthesis of INSM1

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R-HSA-210913
Type
Reaction [omitted]
Species
Homo sapiens
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The INSM1 gene is transcribed, its mRNA is translated, and the protein product is transported to the nucleus. INSM1 transcription requires the activity of the NEUROG3 transcription factor (Mellitzer et al. 2006).

Literature References
PubMed ID Title Journal Year
16511571 IA1 is NGN3-dependent and essential for differentiation of the endocrine pancreas

Mellitzer, G, Bonne, S, Luco, RF, Van De Casteele, M, Lenne-Samuel, N, Collombat, P, Mansouri, A, Lee, J, Lan, M, Pipeleers, D, Nielsen, FC, Ferrer, J, Gradwohl, G, Heimberg, H

EMBO J 2006
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