NRAGE activates JNK

Stable Identifier
R-HSA-205132
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol, plasma membrane
ReviewStatus
5/5
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NRAGE activates JNK
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The NGF:p75:NRAGE complex promotes threonine and tyrosine phosphorylation, and activation of JNK, by an unknown mechanism.
Participants
Input
Output
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as an event of
Catalyst Activity

JUN kinase activity of NGF:p75NTR:NRAGE [plasma membrane]

Physical Entity
NGF:p75NTR:NRAGE [plasma membrane] (Homo sapiens)
Activity
JUN kinase activity (GO:0004705)
Inferred From
Nrage activates Jnk1 (Rattus norvegicus)
Authored
Nasi, S  (2006-10-10)
Annibali, D  (2006-10-10)
Reviewed
Friedman, WJ  (2008-05-20)
Chao, MV  (2008-05-28)
Created
Jassal, B  (2007-12-06)
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