WWTR1 (TAZ) binds TEAD

Stable Identifier
R-HSA-2032781
Type
Reaction [binding]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
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In the nucleus the WWTR1 (TAZ) transcriptional coactivator can bind any one of the four TEAD transcription factors to form a complex. The stoichiometry of this complex is unknown (Chan et al. 2009; Zhang et al. 2009).
Literature References
PubMed ID Title Journal Year
19324877 TEAD transcription factors mediate the function of TAZ in cell growth and epithelial-mesenchymal transition

Lei, Q, Guan, KL, Xiong, Y, Liu, CY, Zhang, H, Zhao, B, Zha, ZY, Yao, J, Zhao, S

J Biol Chem 2009
19324876 TEADs mediate nuclear retention of TAZ to promote oncogenic transformation

Lim, CJ, Hong, W, Loo, LS, Huang, C, Chan, SW, Chong, YF

J Biol Chem 2009
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