CTSZ [plasma membrane]

Stable Identifier
R-HSA-2022345
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Cathepsin Z, Cathepsin X, CATZ_HUMAN
Locations in the PathwayBrowser
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General

After secretion Cathepsin Z (Cathepsin X) is extracellular and associated with the plasma membrane.

Literature References
PubMed ID Title Journal Year
16376371 An enzyme-linked immunosorbent assay for human cathepsin X, a potential new inflammatory marker

Nägler, DK, Lechner, AM, Oettl, A, Kozaczynska, K, Scheuber, HP, Gippner-Steppert, C, Bogner, V, Biberthaler, P, Jochum, M

J Immunol Methods 2006
17065156 RGD-dependent binding of procathepsin X to integrin alphavbeta3 mediates cell-adhesive properties

Lechner, AM, Assfalg-Machleidt, I, Zahler, S, Stoeckelhuber, M, Machleidt, W, Jochum, M, Nägler, DK

J Biol Chem 2006
External Reference Information
External Reference
UniProt:Q9UBR2 CTSZ
Gene Names
CTSZ
Chain
signal peptide:1-23, propeptide:24-61, chain:62-303
Reference Genes
BioGPS Gene:1522 CTSZ
COSMIC (genes):CTSZ CTSZ
CTD Gene:1522 CTSZ
dbSNP Gene:1522 CTSZ
ENSEMBL:ENSG00000101160 CTSZ
HGNC:2547 CTSZ
KEGG Gene (Homo sapiens):1522 CTSZ
Monarch:1522 CTSZ
NCBI Gene:1522 CTSZ
OMIM:603169 CTSZ
UCSC:Q9UBR2 CTSZ
Reference Transcript
Other Identifiers
11726594_at
1522
16920762
1DEU
1EF7
210042_s_at
25114
32514_s_at
3911766
3911768
3911769
3911771
3911774
3911778
3911780
3911781
3911782
3911783
3911784
49876
53504
8067279
A_23_P40240
AAC39839
AAC61477
AAC63141
AAF13145
AAF13148
AAH42168
AF009923
AF032906
AF073890
AF136273
AF136274
AF136275
AF136276
AK314931
AL109840
BAG37437
BC042168
CAB025114
CCDS13474
CH471077
CTSZ
CTSZ-201
EAW75448
ENSG00000101160
ENSP00000217131
ENST00000217131
ENST00000217131.5
EntrezGene:1522
EntrezGene:CTSZ
g3650497_3p_at
GO:0000139
GO:0002003
GO:0002376
GO:0003013
GO:0003674
GO:0004180
GO:0004197
GO:0005515
GO:0005575
GO:0005576
GO:0005615
GO:0005622
GO:0005623
GO:0005737
GO:0005764
GO:0005773
GO:0005783
GO:0005788
GO:0005794
GO:0005886
GO:0006508
GO:0006810
GO:0006888
GO:0008150
GO:0008219
GO:0008233
GO:0008234
GO:0008283
GO:0009056
GO:0009986
GO:0010757
GO:0010977
GO:0016192
GO:0016787
GO:0022607
GO:0030134
GO:0030154
GO:0030426
GO:0031012
GO:0031410
GO:0032091
GO:0033116
GO:0034641
GO:0035580
GO:0043226
GO:0043231
GO:0043312
GO:0043525
GO:0048208
GO:0048856
GO:0051603
GO:0051604
GO:0060441
GO:0061024
GO:0062023
GO:0065003
GO:0070062
GO:0099738
GO:1901214
GO:1904813
GO:2000179
HGNC:2547
HPA049876
HPA053504
ILMN_1666269
IPR000668
IPR025661
IPR033157
IPR038765
MIM:603169
NM_001336
NP_001327
PF00112
PH_hs_0013327
PR00705
SM00645
TC20000992.hg
UPI000000D9CC
Other forms of this molecule
(Glc)3(GlcNAc)2(Man)9-CTSZ [COPII-coated ER to Golgi transport vesicle]
(Glc)3(GlcNAc)2(Man)9-CTSZ [endoplasmic reticulum lumen]
(Glc)3(GlcNAc)2(Man)9-CTSZ [endoplasmic reticulum-Golgi intermediate compartment membrane]
CTSZ [ficolin-1-rich granule lumen]
CTSZ [extracellular region]
CTSZ [specific granule lumen]
CTSZ [lysosomal lumen]
CTSZ [Golgi lumen]
Inferred To
CTSZ [plasma membrane] (Canis familiaris)
CTSZ [plasma membrane] (Danio rerio)
CTSZ [plasma membrane] (Mus musculus)
CTSZ [plasma membrane] (Rattus norvegicus)
CTSZ [plasma membrane] (Sus scrofa)
CTSZ [plasma membrane] (Xenopus tropicalis)
Cross References
RefSeq
ZINC - Investigational
OpenTargets
ZINC - Substances
GeneCards
ZINC target
PRO
ZINC - Predictions - Purchasable
PDB
Interactors (19)