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NGFR(273-427) [nucleoplasm]
Stable Identifier
R-HSA-197473
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
p75NTR intracellular domain, Tumor necrosis factor receptor superfamily member 16, TR16_HUMAN, NGFR
Icon
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Death Receptor Signalling (Homo sapiens)
p75 NTR receptor-mediated signalling (Homo sapiens)
Regulated proteolysis of p75NTR (Homo sapiens)
Part of the ICD migrates to the nucleus (Homo sapiens)
NGFR(273-427) [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:P08138 NGFR
Gene Names
NGFR, TNFRSF16
Chain
signal peptide:1-28, chain:29-427
Reference Genes
BioGPS Gene:4804 NGFR
COSMIC (genes):NGFR NGFR
CTD Gene:4804 NGFR
dbSNP Gene:4804 NGFR
ENSEMBL:ENSG00000064300 NGFR
HGNC:7809 NGFR
KEGG Gene (Homo sapiens):4804 NGFR
Monarch:4804 NGFR
NCBI Gene:4804 NGFR
OMIM:162010 NGFR
UCSC:P08138 NGFR
Reference Transcript
RefSeq:NM_002507.3 NGFR
Other Identifiers
0003990180
11723398_at
11747159_a_at
143
1673_at
16835592
1995
205858_at
2N80
2N83
2N97
3725686
3725687
3725694
3725699
3725702
3725705
3725706
3725707
3725708
3EWV
4765
4804
5ZGG
8008201
A_23_P389897
AAA36363
AAB59544
AAH50309
AC006487
AC015656
AK303278
AK313654
BAG36408
BAG64358
BC050309
CAB000143
CAB001995
CCDS11549
CH471109
EAW94677
ENSG00000064300
ENSP00000172229
ENSP00000421731
ENST00000172229
ENST00000172229.7
ENST00000504201
ENST00000504201.1
EntrezGene:4804
EntrezGene:NGFR
g4505392_3p_at
GE57836
GO:0000902
GO:0001540
GO:0001678
GO:0003674
GO:0004888
GO:0005035
GO:0005515
GO:0005516
GO:0005575
GO:0005576
GO:0005622
GO:0005623
GO:0005634
GO:0005654
GO:0005737
GO:0005768
GO:0005829
GO:0005886
GO:0005887
GO:0006810
GO:0006886
GO:0006915
GO:0006919
GO:0007165
GO:0007266
GO:0007275
GO:0007399
GO:0008150
GO:0008219
GO:0008283
GO:0009058
GO:0009986
GO:0015026
GO:0015031
GO:0016020
GO:0016021
GO:0017137
GO:0019899
GO:0030154
GO:0030426
GO:0031293
GO:0031410
GO:0031625
GO:0032922
GO:0034641
GO:0038023
GO:0042592
GO:0042593
GO:0042995
GO:0043065
GO:0043066
GO:0043121
GO:0043154
GO:0043197
GO:0043204
GO:0043226
GO:0043281
GO:0048011
GO:0048406
GO:0048511
GO:0048646
GO:0048856
GO:0050771
GO:0050772
GO:0051402
GO:1900182
GO:1902895
GO:1903588
GO:1904646
HGNC:7809
HPA004765
ILMN_1752658
IPR000488
IPR001368
IPR011029
IPR022325
IPR034046
IPR041448
M14764
M14764_at
M21621
MIM:162010
NGFR
NGFR-201
NGFR-202
NM_002507
NP_002498
PF00020
PF00531
PF18422
PH_hs_0025025
PR01966
SM00005
SM00208
TC17000645.hg
UPI0000049854
UPI00017A841C
Participant Of
output
Part of the ICD migrates to the nucleus
Other forms of this molecule
NGFR(29-250) [extracellular region]
NGFR(251-427) [endosome]
NGFR(251-272) [plasma membrane]
NGFR(251-427) [plasma membrane]
NGFR(273-427) [cytosol]
NGFR [plasma membrane]
Inferred To
NGFR(273-427) [nucleoplasm] (Bos taurus)
NGFR(273-427) [nucleoplasm] (Canis familiaris)
NGFR(273-427) [nucleoplasm] (Danio rerio)
NGFR(273-427) [nucleoplasm] (Mus musculus)
NGFR(273-427) [nucleoplasm] (Rattus norvegicus)
NGFR(273-427) [nucleoplasm] (Sus scrofa)
NGFR(273-427) [nucleoplasm] (Xenopus tropicalis)
Cross References
RefSeq
NP_002498.1
OpenTargets
ENSG00000064300
ZINC - Substances
TNR16_HUMAN
GeneCards
P08138
ZINC target
P08138
PRO
P08138
Orphanet
24760
ZINC - Predictions - Purchasable
TNR16_HUMAN
PDB
5ZGG
,
2N97
,
3EWV
,
2N80
,
2N83
Interactors (8)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P25233 NECD
0.602
3
UniProt:Q9CPR8
1
NSMCE3 [nucleoplasm]
(R-MMU-2993761)
0.602
3
UniProt:Q96FE5 LINGO1
1
LINGO1 [plasma membrane]
(R-HSA-3006563)
0.589
2
UniProt:Q9Y467 SALL2
0.581
3
UniProt:P05067 APP
20
APP-C99 [cytosol]
(R-HSA-9617603)
APP(18-770) [trans-Golgi network membrane]
(R-HSA-5229136)
APP(18-687) [extracellular region]
(R-HSA-9010033)
APP(688-770) [plasma membrane]
(R-HSA-9010028)
APP(18-770) [Golgi lumen]
(R-HSA-8871509)
APP(18-770) [plasma membrane]
(R-HSA-9010038)
APP(18-671) [endosome lumen]
(R-HSA-5693003)
APP(714-770) [endosome lumen]
(R-HSA-6783325)
APP(712-770) [endosome lumen]
(R-HSA-6783331)
APP(672-770) [endosome lumen]
(R-HSA-9010082)
APP(672-713) [endosome lumen]
(R-HSA-5692993)
APP(672-711) [endosome lumen]
(R-HSA-6783333)
APP(18-770) [endosome lumen]
(R-HSA-5229077)
APP(18-770) [extracellular region]
(R-HSA-49335)
APP(18-770) [platelet alpha granule lumen]
(R-HSA-139835)
APP(672-711) [cytosol]
(R-HSA-877188)
APP(672-711) [extracellular region]
(R-HSA-976740)
p-APP [endoplasmic reticulum lumen]
(R-HSA-8957012)
APP [endoplasmic reticulum lumen]
(R-HSA-8956696)
APP(672-713) [extracellular region]
(R-HSA-879340)
0.558
2
UniProt:P33681 CD80
1
CD80 [plasma membrane]
(R-HSA-179789)
0.544
3
UniProt:P01138-PRO_0000019600 NGF
0.544
2
UniProt:P01138 NGF
7
NGF(19-241) [extracellular region]
(R-HSA-187033)
NGF [Golgi lumen]
(R-HSA-166515)
NGF [cytosol]
(R-HSA-190059)
NGF(1-241) [endoplasmic reticulum lumen]
(R-HSA-187026)
NGF(19-241) [Golgi lumen]
(R-HSA-187036)
NGF(19-241) [endoplasmic reticulum lumen]
(R-HSA-187047)
NGF [extracellular region]
(R-HSA-167034)
0.544
2
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