Reactome | GDI1 [cytosol]

GDI1 [cytosol]

Stable Identifier

R-HSA-195106

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

GDI1/Rab GDI alpha

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P31150 GDI1

Gene Names

GDI1, GDIL, OPHN2, RABGDIA, XAP4

Chain

chain:1-447

Reference Genes

BioGPS Gene:2664 GDI1

COSMIC (genes):GDI1 GDI1

CTD Gene:2664 GDI1

dbSNP Gene:2664 GDI1

ENSEMBL:ENSG00000203879 GDI1

ENSEMBL_homo_sapiens_GENE:ENSG00000203879.12 GDI1

HGNC:4226 GDI1

KEGG Gene (Homo sapiens):2664 GDI1

Monarch:2664 GDI1

NCBI Gene:2664 GDI1

OMIM:300104 GDI1

UCSC:P31150 GDI1

Reference Transcript

RefSeq:NM_001493.2 GDI1

Other Identifiers

11719663_s_at

11719664_a_at

11747307_a_at

11752718_a_at

201864_PM_at

201864_at

2664

36152_at

3996405

3996406

3996407

3996411

3996412

3996414

3996416

3996418

3996420

3996422

3996423

3996425

3996426

3996428

3996429

3996431

3996432

8170891

89908_f_at

A_14_P111911

A_23_P45496

GE60048

GO:0005092

GO:0005093

GO:0005096

GO:0005515

GO:0005737

GO:0005794

GO:0005829

GO:0006886

GO:0007165

GO:0007264

GO:0015031

GO:0016192

GO:0023052

GO:0030154

GO:0030424

GO:0030496

GO:0031267

GO:0032482

GO:0032991

GO:0043025

GO:0043209

GO:0043226

GO:0045773

GO:0048856

GO:0050771

GO:0051592

GO:0090315

GO:0098772

GO:0099523

HMNXSV003035431

PH_hs_0004253

X79353_at

g4503970_3p_at

Participates

as a member of

GDIs,CHMs [cytosol] (Homo sapiens)

Inferred To

Gdi [cytosol] (Drosophila melanogaster)

GDI1 [cytosol] (Bos taurus)

GDI1 [cytosol] (Canis familiaris)

GDI1 [cytosol] (Dictyostelium discoideum)

GDI1 [cytosol] (Plasmodium falciparum)

GDI1 [cytosol] (Saccharomyces cerevisiae)

GDI1 [cytosol] (Sus scrofa)

gdi1 [cytosol] (Schizosaccharomyces pombe)

gdi1 [cytosol] (Xenopus tropicalis)

gdi-1 [cytosol] (Caenorhabditis elegans)

Gdi1 [cytosol] (Mus musculus)

Gdi1 [cytosol] (Rattus norvegicus)

Cross References

RefSeq

NP_001484.1

OpenTargets

ENSG00000203879

HPA

ENSG00000203879-GDI1

GeneCards

P31150

Ensembl

ENSP00000394071, ENST00000447750, ENSG00000203879

PRO

P31150

Pharos - Targets

P31150

Orphanet

16115

HMDB Protein

HMDBP01782

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P13569 CFTR	17	PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) CFTR [lysosomal membrane] (R-HSA-5627279) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [endosome membrane] (R-HSA-6782965) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) ub-CFTR F508del [cytosol] (R-HSA-8866838) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) CFTR G542* [plasma membrane] (R-HSA-5678986) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR [plasma membrane] (R-HSA-383188) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730)	0.615	7
UniProt:P51149 RAB7A	7	RAB7A [secretory granule membrane] (R-HSA-6804969) RAB7A [plasma membrane] (R-HSA-6804990) RAB7A [cytosol] (R-HSA-8870415) RAB7A [phagocytic vesicle membrane] (R-HSA-9636586) RAB7A [lysosomal membrane] (R-HSA-2213231) GGC-RAB7A [cytosol] (R-HSA-8870438) GGC-RAB7A [lysosomal membrane] (R-HSA-8877454)	0.527	2
UniProt:P20339 RAB5A	7	GGC-RAB5A [clathrin-coated endocytic vesicle membrane] (R-HSA-8871125) GGC-RAB5A [early endosome membrane] (R-HSA-8875323) GGC-RAB5A [cytosol] (R-HSA-8870432) RAB5A [cytosol] (R-HSA-2201187) GGC-RAB5A [macropinosome membrane] (R-HSA-9837697) RAB5A [endosome membrane] (R-HSA-452257) RAB5A [early endosome membrane] (R-HSA-2130175)	0.527	3

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