NRIF binds to p75NTR

Stable Identifier
R-HSA-193677
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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NRIF is a ubiquitously expressed zinc finger protein of the Kruppel family that may transduce cell death signals during development and functions in association with TRAF6 to induce activation of JNK. NRIF-induced cell death through p75NTR requires p53 and NRIF nuclear translocation, which is modulated by TRAF6-mediated polyubiquitination of NRIF at lysine 63.

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