Transport of MHC I:Nef:AP-1:PACS-1 Complex

Stable Identifier
R-HSA-182286
Type
Reaction [transition]
Species
Homo sapiens
Related Species
Human immunodeficiency virus 1
Compartment
ReviewStatus
5/5
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The complex of Nef, major histocompatibility complex class I molecules, PACS-1 and AP-1 is transported from the trans-Golgi network to an endosome, where the MHC I complex will be degraded.
Literature References
PubMed ID Title Journal Year
15569716 HIV-1 Nef disrupts MHC-I trafficking by recruiting AP-1 to the MHC-I cytoplasmic tail

Filzen, TM, Williams, M, Roeth, JF, Collins, KL, Kasper, MR

J Cell Biol 2004
Participants
Participates
Disease
Name Identifier Synonyms
Human immunodeficiency virus infectious disease DOID:526 HIV infection
Authored
Reviewed
Created
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