Rev multimer-bound HIV mRNA associates with Crm1

Stable Identifier
R-HSA-180885
Type
Reaction [binding]
Species
Homo sapiens
Related Species
Human immunodeficiency virus 1
Compartment
ReviewStatus
5/5
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CRM1 associates directly with Rev through the Rev nuclear export signal (NES) domain and acts as the nuclear export receptor for the Rev-RRE ribonucleoprotein complex.
Literature References
PubMed ID Title Journal Year
9837918 The specificity of the CRM1-Rev nuclear export signal interaction is mediated by RanGTP

Jensen, TH, Englmeier, L, Nilsson, J, Askjaer, P, Kjems, J

J Biol Chem 1998
Participants
Participates
Disease
Name Identifier Synonyms
Human immunodeficiency virus infectious disease DOID:526 HIV infection
Authored
Reviewed
Created
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