Reactome | Association of cell cycle proteins with the APC/C:Cdh1 complex

Association of cell cycle proteins with the APC/C:Cdh1 complex

Stable Identifier

R-HSA-174088

Type

Reaction [binding]

Species

Homo sapiens

Compartment

cytosol

ReviewStatus

5/5

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Association of cell cycle proteins with the APC/C:Cdh1 complex

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The APC/C:Cdh1 complex recognizes substrates containing a D box, a KEN box (Pfleger and Kirschner, 2000) or a D box activated (DAD) domain (Castro et al., 2002).

Literature References

PubMed ID	Title	Journal	Year
10733526	The KEN box: an APC recognition signal distinct from the D box targeted by Cdh1 Kirschner, MW, Pfleger, CM	Genes Dev	2000
12446569	The D-Box-activating domain (DAD) is a new proteolysis signal that stimulates the silent D-Box sequence of Aurora-A Lorca, T, Bernis, C, Prigent, C, Vigneron, S, Castro, A, Labbe, JC	EMBO Rep	2002