Influenza Virus Induced Apoptosis

Stable Identifier
R-HSA-168277
Type
Pathway
Species
Homo sapiens
Related Species
Influenza A virus
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Influenza Virus Induced Apoptosis
Click the image above or here to open this pathway in the Pathway Browser
Influenza A virus induces apoptosis in a variety of ways including activation of host TGF-beta by expression of viral NA, M1 and M2 proteins, and by the binding of viral PB1-F2 to host mitochondrial adenine nucleotide translocator 3 (ANT3).
Literature References
PubMed ID Title Journal Year
0 Orthomyxoviridae: The Viruses and Their Replication

Shaw, ML, Palese, P

Fields Virology, 5th edition D.M. Knipe and P.M. Howley, Editors. 2006, Lippencott Williams and Wilkins: Philadelphia ISBN-10: 0-7817-6060-7 2001
Participants
Events
Participates
as an event of
Event Information
Go Biological Process
induction by virus of host immune response (0046730)
Disease
Name Identifier Synonyms
influenza DOID:8469 Influenza with other manifestations (disorder), Influenza with other manifestations NOS (disorder), flu, Influenza with other manifestations, Influenza with non-respiratory manifestation (disorder), influenza with non-respiratory manifestation
Authored
Gillespie, ME  (2013-11-18)
Reviewed
Gale M, Jr  (2004-05-12)
Created
Gillespie, ME  (2005-11-14)
Cite Us!