Myristoylation of Nef

Stable Identifier
R-HSA-162914
Type
Reaction [transition]
Species
Homo sapiens
Related Species
Human immunodeficiency virus 1
Compartment
cytosol
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Myristoylation of Nef
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
Nef amino terminal myristoylation has been shown to be critical for many of Nef's functions. As expected myristoylated Nef can be identified as co-fractionating with cell membranes and cytoskeletal components.
Literature References
Participants
Input
Output
Participates
as an event of
Event Information
Go Biological Process
N-terminal protein myristoylation (0006499)
Catalyst Activity

myristoyltransferase activity of NMT 1 [cytosol]

Physical Entity
NMT1 [cytosol] (Homo sapiens)
Activity
myristoyltransferase activity (GO:0019107)
Disease
Name Identifier Synonyms
Human immunodeficiency virus infectious disease DOID:526 HIV infection
Created
Joshi-Tope, G  (2005-04-06)
Cite Us!