Recruitment of STATs

Stable Identifier
R-HSA-1433456
Type
Reaction [binding]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
Activation of KIT mediates the recruitment of and association with STAT1alpha, STAT3, STAT5A and STAT5B (Deberry et al. 1997, Brizzi et al. 1999, Rönnstrand 2004).
Literature References
PubMed ID Title Journal Year
11494148 STAT3 activation is required for Asp(816) mutant c-Kit induced tumorigenicity

Ning, ZQ, McGuinness, M, Arceci, RJ, Li, J

Oncogene 2001
10358045 STAT protein recruitment and activation in c-Kit deletion mutants

Yarden, Y, Dentelli, P, Pegoraro, L, Rosso, A, Brizzi, MF

J Biol Chem 1999
9355737 Stat1 associates with c-kit and is activated in response to stem cell factor

DeBerry, C, Linnekin, D, Mou, S

Biochem J 1997
Participants
Participates
Orthologous Events
Authored
Reviewed
Created
Cite Us!