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HGF(32-494) [platelet alpha granule lumen]
Stable Identifier
R-HSA-139866
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
platelet alpha granule lumen
Synonyms
HGF, Hepatocyte growth factor precursor, Scatter factor, SF, Hepatopoeitin A
Locations in the PathwayBrowser
Expand all
Hemostasis (Homo sapiens)
Platelet activation, signaling and aggregation (Homo sapiens)
Response to elevated platelet cytosolic Ca2+ (Homo sapiens)
Platelet degranulation (Homo sapiens)
Exocytosis of platelet alpha granule contents (Homo sapiens)
Platelet alpha granule contents [platelet alpha granule lumen] (Homo sapiens)
Hepatocyte growth factor [platelet alpha granule lumen] (Homo sapiens)
HGF(32-494) [platelet alpha granule lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:P14210 HGF
Gene Names
HGF, HPTA
Chain
signal peptide:1-31, chain:32-494, chain:495-728
Reference Genes
BioGPS Gene:3082 HGF
COSMIC (genes):HGF HGF
CTD Gene:3082 HGF
dbSNP Gene:3082 HGF
ENSEMBL:ENSG00000019991 HGF
HGNC:4893 HGF
KEGG Gene (Homo sapiens):3082 HGF
Monarch:3082 HGF
NCBI Gene:3082 HGF
OMIM:142409 HGF
UCSC:P14210 HGF
Reference Transcript
RefSeq:NM_001010932.2 HGF
RefSeq:XM_017012097.1 HGF
RefSeq:XM_006715956.2 HGF
RefSeq:XM_017012098.1 HGF
RefSeq:XM_011516115.2 HGF
RefSeq:NM_001010934.2 HGF
RefSeq:NM_001010931.2 HGF
RefSeq:NM_000601.5 HGF
RefSeq:NM_001010933.2 HGF
Other Identifiers
0006420110
10333
1095_s_at
11730068_a_at
11732351_at
11732746_a_at
11732747_at
1340_s_at
17059165
1BHT
1GMN
1GMO
1GP9
1NK1
1SHY
1SI5
209960_at
209961_s_at
210755_at
210997_3p_at
210997_at
210998_s_at
2HGF
2QJ2
3058945
3058946
3058947
3058954
3058955
3058956
3058957
3058958
3058959
3058960
3058961
3058963
3058965
3058967
3058968
3058972
3058973
3058974
3058979
3058981
3058982
3058984
3058988
3058989
3082
3HMS
3HMT
3HN4
3MKP
3SP8
40360
44088
4D3C
4K3J
4O3T
4O3U
5COE
5CP9
5CS1
5CS3
5CS5
5CS9
5CSQ
5CT1
5CT2
5CT3
8140556
A0A2R8YEI1
A_23_P93780
A_23_P93787
A_24_P944788
A_33_P3276713
A_33_P3276718
AAA35980
AAA52648
AAA52649
AAA52650
AAA64239
AAA64297
AAC50539
AAC71655
AAG53459
AAG53460
AAH22308
AAH63485
AAI05798
AAI30285
AAI30287
AAO61091
AC004960
AY246560
BAA14348
BC022308
BC063485
BC105797
BC130284
BC130286
C9JDP4
C9JS80
C9WSJ3
C9WSJ4
CAA34387
CAA40802
CAB010333
CCDS47626
CCDS47627
CCDS47628
CCDS47629
CCDS5597
CH236949
D90334
EAL24189
ENSG00000019991
ENSP00000222390
ENSP00000389854
ENSP00000391238
ENSP00000408270
ENSP00000413829
ENST00000222390
ENST00000423064
ENST00000423064.7
ENST00000444829
ENST00000444829.7
ENST00000453411
ENST00000453411.6
ENST00000457544
ENST00000457544.7
ENST00000644543.1
EntrezGene:3082
EntrezGene:HGF
g1378041_3p_at
g184029_3p_a_at
g184029_3p_at
g184031_3p_a_at
GE62425
GO:0000165
GO:0000187
GO:0000278
GO:0000902
GO:0001837
GO:0001889
GO:0001934
GO:0002576
GO:0003674
GO:0004252
GO:0005515
GO:0005575
GO:0005576
GO:0005615
GO:0005622
GO:0005623
GO:0005737
GO:0006259
GO:0006464
GO:0006508
GO:0006810
GO:0006914
GO:0006950
GO:0007005
GO:0007049
GO:0007165
GO:0007267
GO:0008083
GO:0008150
GO:0008219
GO:0008233
GO:0008283
GO:0009056
GO:0009058
GO:0010507
GO:0014068
GO:0016020
GO:0016192
GO:0019221
GO:0030154
GO:0030212
GO:0030335
GO:0031093
GO:0031100
GO:0031410
GO:0031643
GO:0032715
GO:0032733
GO:0033137
GO:0034641
GO:0035729
GO:0040011
GO:0042056
GO:0042802
GO:0043066
GO:0043154
GO:0043226
GO:0044281
GO:0045669
GO:0045766
GO:0045944
GO:0046982
GO:0048012
GO:0048646
GO:0048856
GO:0048870
GO:0050673
GO:0050728
GO:0050731
GO:0050877
GO:0050918
GO:0051450
GO:0051897
GO:0060326
GO:0060665
GO:0070572
GO:0090201
GO:1900744
GO:1901299
GO:1902042
GO:1902947
GO:2000573
HGF
HGF-201
HGF-205
HGF-206
HGF-208
HGF-209
HGNC:4893
HPA040360
HPA044088
Hs.809.0.S3_3p_at
ILMN_1757838
ILMN_1790149
ILMN_1801586
ILMN_1896012
IPR000001
IPR001254
IPR001314
IPR003609
IPR009003
IPR013806
IPR018056
IPR024174
IPR027284
IPR038178
L02931
M29145
M55379
M60718
M73239
M73239_s_at
M73240
M75966
M75967
M75968
M75969
M75971
M75972
M75973
M75974
M75975
M75976
M75977
M75978
M75979
M75980
M75981
M75982
M75983
M77227
MIM:142409
MIM:608265
NM_000601
NM_001010931
NM_001010932
NM_001010933
NM_001010934
NP_000592
NP_001010931
NP_001010932
NP_001010933
NP_001010934
PF00024
PF00051
PF00089
PH_hs_0018966
PR00018
PR00722
SM00020
SM00130
SM00473
TC07001562.hg
U46010
UPI000000D92B
UPI000006F886
UPI00000720D2
UPI0000073BF9
UPI0000146316
X16323
X57574
XM_006715956
XM_011516115
XM_017012097
XM_017012098
XP_006716019
XP_011514417
XP_016867586
XP_016867587
Participant Of
hasComponent
Hepatocyte growth factor [platelet alpha granule lumen]
Other forms of this molecule
HGF(495-728) [platelet alpha granule lumen]
pro-HGF [extracellular region]
HGF(495-728) [extracellular region]
HGF(32-494) [extracellular region]
Inferred To
HGF(32-494) [platelet alpha granule lumen] (Canis familiaris)
HGF(32-494) [platelet alpha granule lumen] (Danio rerio)
HGF(32-494) [platelet alpha granule lumen] (Gallus gallus)
HGF(32-494) [platelet alpha granule lumen] (Mus musculus)
HGF(32-494) [platelet alpha granule lumen] (Rattus norvegicus)
HGF(32-494) [platelet alpha granule lumen] (Sus scrofa)
HGF(32-494) [platelet alpha granule lumen] (Xenopus tropicalis)
Cross References
RefSeq
NP_001010934.1
,
NP_001010933.1
,
XP_011514417.1
,
XP_016867586.1
,
XP_006716019.1
,
XP_016867587.1
,
NP_001010932.1
,
NP_001010931.1
,
NP_000592.3
OpenTargets
ENSG00000019991
GeneCards
P14210
ZINC - Substances
HGF_HUMAN
ZINC target
P14210
PRO
P14210
Orphanet
18471
ZINC - Predictions - Purchasable
HGF_HUMAN
PDB
4O3U
,
2HGF
,
1SHY
,
3HMS
,
5CS3
,
3SP8
,
5CP9
,
4K3J
,
1BHT
,
1SI5
,
5CSQ
,
5CT1
,
3HMT
,
5CS5
,
1GMO
,
2QJ2
,
5CT2
,
1GMN
,
5CS9
,
3HN4
,
1NK1
,
5COE
,
4O3T
,
1GP9
,
4D3C
,
5CT3
,
5CS1
,
3MKP
Interactors (5)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P08581 MET
7
p-Y1234,Y1235,Y1356-MET [plasma membrane]
(R-HSA-6807014)
p-Y1349,Y1356-MET [plasma membrane]
(R-HSA-6807032)
MonoUb-K,p-Y1234,Y1235,Y1349,Y1356-MET [plasma membrane]
(R-HSA-8875181)
MonoUb-K,p-Y1003,4Y-MET [plasma membrane]
(R-HSA-8875180)
p-Y1003,4Y-MET [plasma membrane]
(R-HSA-8874689)
MET [plasma membrane]
(R-HSA-419603)
p-Y1234,Y1235,Y1349,Y1356-MET [plasma membrane]
(R-HSA-6806973)
0.851
7
UniProt:P14210 HGF
5
HGF(495-728) [platelet alpha granule lumen]
(R-HSA-141764)
HGF(32-494) [platelet alpha granule lumen]
(R-HSA-139866)
pro-HGF [extracellular region]
(R-HSA-6800218)
HGF(495-728) [extracellular region]
(R-HSA-141767)
HGF(32-494) [extracellular region]
(R-HSA-56497)
0.623
2
UniProt:P16056
7
phospho-p-Y1234,Y1235,Y1356-MET [plasma membrane]
(R-MMU-6807014)
phospho-p-Y1349,Y1356-MET [plasma membrane]
(R-MMU-6807032)
phospho-MonoUb-K,p-Y1234,Y1235,Y1349,Y1356-MET [plasma membrane]
(R-MMU-8875181)
phospho-MonoUb-K,p-Y1003,4Y-MET [plasma membrane]
(R-MMU-8875180)
phospho-p-Y1003,4Y-MET [plasma membrane]
(R-MMU-8874689)
MET [plasma membrane]
(R-MMU-419603)
phospho-p-Y1234,Y1235,Y1349,Y1356-MET [plasma membrane]
(R-MMU-6806973)
0.558
2
UniProt:Q6UY14-3 ADAMTSL4
0.556
3
UniProt:P50222 MEOX2
0.556
3
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