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NCOR1 [cytosol]
Stable Identifier
R-HSA-1253310
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Nuclear receptor corepressor 1, NCOR1_HUMAN
Icon
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by ERBB4 (Homo sapiens)
Nuclear signaling by ERBB4 (Homo sapiens)
ERBB4s80 binds TAB2:NCOR1 complex (Homo sapiens)
ERBB4s80:TAB2:NCOR1 [cytosol] (Homo sapiens)
TAB2:NCOR1 [cytosol] (Homo sapiens)
NCOR1 [cytosol] (Homo sapiens)
TAB2:NCOR1 [cytosol] (Homo sapiens)
NCOR1 [cytosol] (Homo sapiens)
ERBB4s80:TAB2:NCOR1 complex translocates to the nucleus (Homo sapiens)
ERBB4s80:TAB2:NCOR1 [cytosol] (Homo sapiens)
TAB2:NCOR1 [cytosol] (Homo sapiens)
NCOR1 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:O75376 NCOR1
Gene Names
NCOR1, KIAA1047
Chain
chain:1-2440
Reference Genes
BioGPS Gene:9611 NCOR1
COSMIC (genes):NCOR1 NCOR1
CTD Gene:9611 NCOR1
dbSNP Gene:9611 NCOR1
ENSEMBL:ENSG00000141027 NCOR1
ENSEMBL_homo_sapiens_GENE:ENSG00000141027.23 NCOR1
HGNC:7672 NCOR1
KEGG Gene (Homo sapiens):9611 NCOR1
Monarch:9611 NCOR1
NCBI Gene:9611 NCOR1
OMIM:600849 NCOR1
UCSC:O75376 NCOR1
Reference Transcript
RefSeq:NM_006311.3 NCOR1
RefSeq:XM_011524086.2 NCOR1
RefSeq:NM_001190440.1 NCOR1
RefSeq:NM_001190438.1 NCOR1
Other Identifiers
11725115_a_at
11725116_a_at
11744884_a_at
11751590_a_at
11759574_a_at
16841707
200854_PM_at
200854_at
200855_PM_at
200855_at
200856_PM_x_at
200856_x_at
200857_PM_s_at
200857_s_at
3003735
3003754
3714866
3746883
3746884
3746885
3746886
3746889
3746890
3746894
3746898
3746899
3746900
3746903
3746904
3746906
3746908
3746909
3746912
3746913
3746914
3746915
3746917
3746921
3746922
3746923
3746924
3746926
3746927
3746928
3746929
3746930
3746931
3746932
3746934
3746935
3746936
3746937
3746938
3746942
3746943
3746944
3746946
3746947
3746948
3746950
3746951
3746953
3746955
3746956
3746957
3746960
3746961
3746962
3746967
3746968
3746972
3746974
3746976
3746979
3746980
3746981
3746982
3746985
3746986
3746987
3746988
3747162
3880943
3902262
3902268
63388_at
75470_at
8005733
8012961
9611
A_23_P141651
A_24_P204214
GE53714
GE81621
GE85063
GE88675
GO:0000118
GO:0000122
GO:0000785
GO:0000976
GO:0003677
GO:0003714
GO:0005515
GO:0005634
GO:0005654
GO:0005694
GO:0005829
GO:0005856
GO:0005975
GO:0006091
GO:0006325
GO:0006351
GO:0006355
GO:0006629
GO:0007010
GO:0007059
GO:0016020
GO:0016922
GO:0017053
GO:0023052
GO:0042826
GO:0043226
GO:0045475
GO:0045820
GO:0045892
GO:0045922
GO:0046329
GO:0046966
GO:0048511
GO:0051225
GO:0055086
GO:0060766
GO:0061629
GO:0072686
GO:0140110
GO:1901135
GO:1902894
HMNXSV003052362
Hs.144904.0.S2_3p_at
Hs.144904.0.S3_3p_at
Hs.144904.0.S4_3p_at
Hs.144904.0.S4_3p_x_at
ILMN_2186369
PH_hs_0008590
TC17001171.hg
g5454137_3p_a_at
p33516
Participates
as a component of
TAB2:NCOR1 [cytosol] (Homo sapiens)
Other forms of this molecule
NCOR1 [nucleoplasm]
Cross References
RefSeq
XP_011522388.1
,
NP_006302.2
,
NP_001177369.1
,
NP_001177367.1
OpenTargets
ENSG00000141027
GeneCards
O75376
HPA
ENSG00000141027-NCOR1
Ensembl
ENSG00000141027
,
ENST00000395848
,
ENSP00000379192
,
ENSP00000268712
,
ENST00000395851
,
ENSP00000379189
,
ENST00000268712
PRO
O75376
Pharos - Targets
O75376
Orphanet
25756
PDB
3H52
,
2EQR
,
6Y17
,
3KMZ
,
6WMQ
,
8D8I
,
6WMS
,
6XXS
,
4WVD
,
8DKV
,
3N00
,
6XYX
,
6XZZ
,
6ONI
,
6ZBU
,
8AS9
,
8DKN
,
4MDD
Interactors (25)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P10276 RARA
3
SUMO2-K166,177,399-p-S219,269-RARA [nucleoplasm]
(R-HSA-5334830)
polySUMO2-K166,K171,K399-RARA [nucleoplasm]
(R-HSA-4341042)
RARA [nucleoplasm]
(R-HSA-446164)
0.802
6
UniProt:O15379 HDAC3
2
HDAC3 [nucleoplasm]
(R-HSA-442464)
Unfolded HDAC3 [cytosol]
(R-HSA-6813777)
0.744
5
UniProt:Q06455 MTG8
0.72
5
UniProt:P12755 SKI
1
SKI [nucleoplasm]
(R-HSA-173473)
0.669
4
UniProt:Q07869 PPARA
2
monoSUMO1-K185-PPARA [nucleoplasm]
(R-HSA-4341099)
PPARA [nucleoplasm]
(R-HSA-400186)
0.658
3
UniProt:P20393 NR1D1
1
NR1D1 [nucleoplasm]
(R-HSA-375499)
0.602
3
UniProt:P37231 PPARG
2
monoSUMO1-K107,K395-PPARG [nucleoplasm]
(R-HSA-4717444)
PPARG [nucleoplasm]
(R-HSA-446172)
0.571
2
UniProt:P10275 AR
4
PolyUb-AR [nucleoplasm]
(R-HSA-6782984)
monoSUMO1-K386,520-AR [nucleoplasm]
(R-HSA-4090320)
AR [nucleoplasm]
(R-HSA-446174)
AR [cytosol]
(R-HSA-5618082)
0.569
4
UniProt:Q13263 TRIM28
2
TRIM28 [nucleoplasm]
(R-HSA-974998)
SUMO1-K554,575,676,750,779,804-TRIM28 [nucleoplasm]
(R-HSA-3782600)
0.556
4
UniProt:Q99719 SEPT5
0.556
3
UniProt:P61764 STXBP1
2
STXBP1 [cytosol]
(R-HSA-6794256)
STXBP1 [plasma membrane]
(R-HSA-2980862)
0.556
3
UniProt:I6L9F6 I6L9F6
0.556
3
IntAct:EBI-25907740 CCSB
0.556
3
UniProt:Q9UJC3 HOOK1
0.556
3
UniProt:Q8IUQ4-2 SIAH1
0.556
3
UniProt:P62937 PPIA
5
PPIA [extracellular exosome]
(R-HSA-6801538)
PPIA [secretory granule lumen]
(R-HSA-6801400)
PPIA [ficolin-1-rich granule lumen]
(R-HSA-6801391)
PPIA [cytosol]
(R-HSA-173123)
PPIA [extracellular region]
(R-HSA-173646)
0.556
3
UniProt:P56524 HDAC4
3
polySUMO2,3-K559-HDAC4 [nucleoplasm]
(R-HSA-4616029)
monoSUMO1-K559-HDAC4 [nucleoplasm]
(R-HSA-4616016)
HDAC4 [nucleoplasm]
(R-HSA-351581)
0.527
2
UniProt:Q13133 NR1H3
1
NR1H3 [nucleoplasm]
(R-HSA-8854957)
0.525
2
UniProt:P55055 NR1H2
3
NR1H2 [cytosol]
(R-HSA-9619753)
polySUMO2,3-K409,K447-NR1H2 [nucleoplasm]
(R-HSA-4720435)
NR1H2 [nucleoplasm]
(R-HSA-375500)
0.525
6
UniProt:Q12824 SMARCB1
1
SMARCB1 [nucleoplasm]
(R-HSA-389261)
0.524
3
UniProt:Q92922 SMARCC1
1
SMARCC1 [nucleoplasm]
(R-HSA-389257)
0.524
3
UniProt:Q8TAQ2 SMARCC2
1
SMARCC2 [nucleoplasm]
(R-HSA-389263)
0.524
3
UniProt:P51532 SMARCA4
1
SMARCA4 [nucleoplasm]
(R-HSA-201686)
0.524
2
UniProt:P06429 VE7
0.488
2
UniProt:P48431 SOX2
1
SOX2 [nucleoplasm]
(R-HSA-452271)
0.483
2
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