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EGLN3 [nucleoplasm]
Stable Identifier
R-HSA-1234104
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Egl nine homolog 3, EGLN3_HUMAN, PHD3
Locations in the PathwayBrowser
Expand all
Cellular responses to external stimuli (Homo sapiens)
Cellular responses to stress (Homo sapiens)
Cellular response to hypoxia (Homo sapiens)
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha (Homo sapiens)
Nuclear PHD1,3 hydroxylates proline residues on EPAS1 (HIF2A) (Homo sapiens)
PHD1,3 [nucleoplasm] (Homo sapiens)
EGLN3:AscH-:Fe2+ [nucleoplasm] (Homo sapiens)
EGLN3 [nucleoplasm] (Homo sapiens)
Nuclear PHD1,3 hydroxylates proline residues on HIF1A (Homo sapiens)
PHD1,3 [nucleoplasm] (Homo sapiens)
EGLN3:AscH-:Fe2+ [nucleoplasm] (Homo sapiens)
EGLN3 [nucleoplasm] (Homo sapiens)
Nuclear PHD1,3 hydroxylates proline residues on HIF3A (Homo sapiens)
PHD1,3 [nucleoplasm] (Homo sapiens)
EGLN3:AscH-:Fe2+ [nucleoplasm] (Homo sapiens)
EGLN3 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9H6Z9 EGLN3
Gene Names
EGLN3
Chain
chain:1-239
Reference Genes
BioGPS Gene:112399 EGLN3
COSMIC (genes):EGLN3 EGLN3
CTD Gene:112399 EGLN3
dbSNP Gene:112399 EGLN3
ENSEMBL:ENSG00000129521 EGLN3
HGNC:14661 EGLN3
KEGG Gene (Homo sapiens):112399 EGLN3
Monarch:112399 EGLN3
NCBI Gene:112399 EGLN3
OMIM:606426 EGLN3
UCSC:Q9H6Z9 EGLN3
Reference Transcript
RefSeq:NM_022073.3 EGLN3
RefSeq:NM_001308103.1 EGLN3
Other Identifiers
0001770670
112399
11733852_at
11757444_a_at
219232_s_at
222847_s_at
3560413
3560414
3560415
3560416
3560417
3560418
3560419
3560421
3560422
3560423
3560437
3560438
3560439
3560440
3560441
3560442
3560443
3560444
3560445
60511_at
64895
7978544
A_23_P360379
A_33_P3256952
AAH10992
AAH64924
AAI05940
AAI11058
AJ310545
AK025273
BAB15101
BC010992
BC064924
BC105939
BC111057
CAC42511
CCDS9646
EGLN3
EGLN3-201
ENSG00000129521
ENSP00000250457
ENST00000250457
ENST00000250457.7
EntrezGene:112399
EntrezGene:EGLN3
F8VR39
F8W1G2
g11545786_3p_a_at
G3V3M1
GE56932
GO:0001666
GO:0003674
GO:0005506
GO:0005515
GO:0005575
GO:0005622
GO:0005623
GO:0005634
GO:0005654
GO:0005737
GO:0005829
GO:0006464
GO:0006520
GO:0006915
GO:0006919
GO:0006950
GO:0006974
GO:0008150
GO:0008219
GO:0008283
GO:0009058
GO:0016491
GO:0016705
GO:0016706
GO:0018126
GO:0018401
GO:0031418
GO:0031545
GO:0034641
GO:0042127
GO:0043167
GO:0043226
GO:0043523
GO:0044281
GO:0046872
GO:0051213
GO:0055114
GO:0061418
HGNC:14661
HPA064895
Hs.18878.0.A1_3p_a_at
ILMN_1667626
IPR005123
IPR006620
MIM:606426
NM_022073
NP_071356
PF13640
PH_hs_0025932
SM00702
TC14001022.hg
UPI000004F8A8
Participant Of
hasComponent
EGLN3:AscH-:Fe2+ [nucleoplasm]
Other forms of this molecule
EGLN3 [cytosol]
Inferred To
EGLN3 [nucleoplasm] (Bos taurus)
EGLN3 [nucleoplasm] (Caenorhabditis elegans)
EGLN3 [nucleoplasm] (Canis familiaris)
EGLN3 [nucleoplasm] (Danio rerio)
EGLN3 [nucleoplasm] (Drosophila melanogaster)
EGLN3 [nucleoplasm] (Gallus gallus)
EGLN3 [nucleoplasm] (Mus musculus)
EGLN3 [nucleoplasm] (Rattus norvegicus)
EGLN3 [nucleoplasm] (Sus scrofa)
EGLN3 [nucleoplasm] (Xenopus tropicalis)
Cross References
RefSeq
NP_001295032.1
,
NP_071356.1
OpenTargets
ENSG00000129521
GeneCards
Q9H6Z9
ZINC - Substances
EGLN3_HUMAN
ZINC target
Q9H6Z9
PRO
Q9H6Z9
Orphanet
24502
ZINC - Predictions - Purchasable
EGLN3_HUMAN
HMDB Protein
HMDBP09212
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q16665 HIF1A
7
2xHP-HIF1A [nucleoplasm]
(R-HSA-1234105)
HN-HIF1A [cytosol]
(R-HSA-1234110)
2xHP-HIF1A [cytosol]
(R-HSA-1234131)
p-Y565,S797-HIF1A [cytosol]
(R-HSA-9634700)
p-Y565-HIF1A [cytosol]
(R-HSA-8857584)
HIF1A [cytosol]
(R-HSA-1234102)
HIF1A [nucleoplasm]
(R-HSA-1234135)
0.881
7
UniProt:Q16659 MAPK6
6
MAPK6 [nucleoplasm]
(R-HSA-5692686)
p-3S,T MAPK6 [nucleoplasm]
(R-HSA-5692665)
p-S189 MAPK6 [nucleoplasm]
(R-HSA-5687015)
p-S189 MAPK6 [cytosol]
(R-HSA-5687019)
MAPK6 [cytosol]
(R-HSA-5686979)
ub-MAPK6 [cytosol]
(R-HSA-5687000)
0.681
6
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