PRDM9 trimethylates histone H3

Stable Identifier
R-HSA-1214188
Type
Reaction [transition]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
As inferred from experiments in vitro with mouse Prdm9, human PRDM9 methylates histone H3 dimethylated at lysine-4 to yield histone H3 trimethylated at lysine-4.
Literature References
PubMed ID Title Journal Year
16292313 A histone H3 methyltransferase controls epigenetic events required for meiotic prophase

Matsui, Y, Yoshida, K, Hayashi, K

Nature 2005
Participants
Participates
Catalyst Activity

histone methyltransferase activity (H3-K4 specific) of PRDM9:DNA [nucleoplasm]

Inferred From
Authored
Reviewed
Created
Cite Us!