Dissociation of LIG3:XRCC1 complex from the BER site

Stable Identifier
R-HSA-110380
Type
Reaction [dissociation]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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Dissociation of LIG3:XRCC1 complex from the BER site
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After the base excision repair is completed, the complex of XRCC1 with LIG3 (DNA ligase 3), and POLB (DNA polymerase beta) dissociate from the repaired DNA (Kubota et al. 1997).
Literature References
PubMed ID Title Journal Year
8978692 Reconstitution of DNA base excision-repair with purified human proteins: interaction between DNA polymerase beta and the XRCC1 protein.

Lindahl, T, Kubota, Y, Nash, RA, Klungland, A, Schär, P, Barnes, DE

EMBO J 1997
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Authored
Matthews, L  (2004-02-03)
Reviewed
Borowiec, JA  (2014-12-22)
Created
Matthews, L  (2004-01-29)
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