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SMURF1 [cytosol]
Stable Identifier
R-GGA-975972
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
cytosol
Synonyms
F1NFN4
Locations in the PathwayBrowser
Expand all
Immune System (Gallus gallus)
Adaptive Immune System (Gallus gallus)
Class I MHC mediated antigen processing & presentation (Gallus gallus)
Antigen processing: Ubiquitination & Proteasome degradation (Gallus gallus)
Interaction of E3 with substrate and E2-Ub complex (Gallus gallus)
Ag-substrate:E3:E2:Ub [cytosol] (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
SMURF1 [cytosol] (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
SMURF1 [cytosol] (Gallus gallus)
Polyubiquitination of substrate (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
SMURF1 [cytosol] (Gallus gallus)
E3:K48-polyubiquitinated substrate [cytosol] (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
SMURF1 [cytosol] (Gallus gallus)
E3:Ub:substrate [cytosol] (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
SMURF1 [cytosol] (Gallus gallus)
Release of E3 from polyubiquitinated substrate (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
SMURF1 [cytosol] (Gallus gallus)
E3:K48-polyubiquitinated substrate [cytosol] (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
SMURF1 [cytosol] (Gallus gallus)
Transfer of Ub from E2 to substrate and release of E2 (Gallus gallus)
Ag-substrate:E3:E2:Ub [cytosol] (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
SMURF1 [cytosol] (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
SMURF1 [cytosol] (Gallus gallus)
E3:Ub:substrate [cytosol] (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
SMURF1 [cytosol] (Gallus gallus)
Signal Transduction (Gallus gallus)
Signaling by Hedgehog (Gallus gallus)
Hedgehog 'on' state (Gallus gallus)
SMURF1/2 dissociates from ub-PTCH1 (Gallus gallus)
SMURF [cytosol] (Gallus gallus)
SMURF1 [cytosol] (Gallus gallus)
ub-PTCH1:SMURF [ciliary membrane] (Gallus gallus)
SMURF [cytosol] (Gallus gallus)
SMURF1 [cytosol] (Gallus gallus)
Signaling by TGFB family members (Gallus gallus)
Signaling by BMP (Gallus gallus)
I-Smad binds to type I receptor, preventing Smad1/5/8 from being activated (Gallus gallus)
BMP:p-BMPR:I-SMAD:SMURF [plasma membrane] (Gallus gallus)
I-SMAD:SMURF [cytosol] (Gallus gallus)
SMURF [cytosol] (Gallus gallus)
SMURF1 [cytosol] (Gallus gallus)
I-SMAD:SMURF [cytosol] (Gallus gallus)
SMURF [cytosol] (Gallus gallus)
SMURF1 [cytosol] (Gallus gallus)
Ubiquitin-dependent degradation controls basal levels of R-Smad1/5/8 (Gallus gallus)
SMURF [cytosol] (Gallus gallus)
SMURF1 [cytosol] (Gallus gallus)
Signaling by TGF-beta Receptor Complex (Gallus gallus)
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) (Gallus gallus)
Disassembly of tight junctions (Gallus gallus)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:Ub-RHOA:SMURF1 [cell junction] (Gallus gallus)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA:SMURF1 [plasma membrane] (Gallus gallus)
SMURF1 [cytosol] (Gallus gallus)
External Reference Information
External Reference
UniProt:F1NFN4
Reference Genes
ENSEMBL:ENSGALG00000004655
Participates
as a candidate of
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
as a component of
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA:SMURF1 [plasma membrane] (Gallus gallus)
as a member of
SMURF [cytosol] (Gallus gallus)
Other forms of this molecule
SMURF1 [nucleoplasm]
Inferred From
SMURF1 [cytosol]
(Homo sapiens)
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