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phospho-TIFA [cytosol]
Stable Identifier
R-GGA-9645512
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
cytosol
Synonyms
p-T9-TIFA, E1BXY0
Locations in the PathwayBrowser
Expand all
Immune System (Gallus gallus)
Innate Immune System (Gallus gallus)
Alpha-protein kinase 1 signaling pathway (Gallus gallus)
ALPK1 phosphorylates TIFA (Gallus gallus)
ALPK1:ADP-heptose:p-T9-TIFA dimer [cytosol] (Gallus gallus)
p-T9-TIFA:p-T9-TIFA [cytosol] (Gallus gallus)
phospho-TIFA [cytosol] (Gallus gallus)
ALPK1:ADP-heptose:TIFA oligomer recruits TRAF6 (Gallus gallus)
ALPK1:ADP-heptose:p-T9-TIFA oligomer [cytosol] (Gallus gallus)
p-T9-TIFA:p-T9-TIFA [cytosol] (Gallus gallus)
phospho-TIFA [cytosol] (Gallus gallus)
ALPK1:ADP-heptose:p-T9-TIFA oligomer:TRAF6 [cytosol] (Gallus gallus)
ALPK1:ADP-heptose:p-T9-TIFA oligomer [cytosol] (Gallus gallus)
p-T9-TIFA:p-T9-TIFA [cytosol] (Gallus gallus)
phospho-TIFA [cytosol] (Gallus gallus)
ALPK1:ADP-heptose:p-T9-TIFA oligomer:K63pUb-TRAF6 oligomer recruits MAP3K7 (TAK1) (Gallus gallus)
ALPK1:ADP-heptose:p-T9-TIFA oligomer:K63-linked pUb-TRAF6 oligomer [cytosol] (Gallus gallus)
ALPK1:ADP-heptose:p-T9-TIFA oligomer [cytosol] (Gallus gallus)
p-T9-TIFA:p-T9-TIFA [cytosol] (Gallus gallus)
phospho-TIFA [cytosol] (Gallus gallus)
ALPK1:ADP-heptose:p-T9-TIFA:polyUb-TRAF6:TAK1:TAB1:TAB2/TAB3: free polyUb chain [cytosol] (Gallus gallus)
ALPK1:ADP-heptose:p-T9-TIFA oligomer:K63-linked pUb-TRAF6 oligomer [cytosol] (Gallus gallus)
ALPK1:ADP-heptose:p-T9-TIFA oligomer [cytosol] (Gallus gallus)
p-T9-TIFA:p-T9-TIFA [cytosol] (Gallus gallus)
phospho-TIFA [cytosol] (Gallus gallus)
Activated TRAF6 synthesizes unanchored polyubiquitin chains upon ALPK1:ADP-heptose stimulation (Gallus gallus)
ALPK1:ADP-heptose:p-T9-TIFA oligomer:K63-linked pUb-TRAF6 oligomer [cytosol] (Gallus gallus)
ALPK1:ADP-heptose:p-T9-TIFA oligomer [cytosol] (Gallus gallus)
p-T9-TIFA:p-T9-TIFA [cytosol] (Gallus gallus)
phospho-TIFA [cytosol] (Gallus gallus)
Auto phosphorylation of TAK1 within the ALPK1:ADP-heptose:p-T9-TIFA:pUb-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 :MAP3K7 complex (Gallus gallus)
ALPK1:ADP-heptose:p-T9-TIFA:polyUb-TRAF6:TAK1:TAB1:TAB2/TAB3: free polyUb chain [cytosol] (Gallus gallus)
ALPK1:ADP-heptose:p-T9-TIFA oligomer:K63-linked pUb-TRAF6 oligomer [cytosol] (Gallus gallus)
ALPK1:ADP-heptose:p-T9-TIFA oligomer [cytosol] (Gallus gallus)
p-T9-TIFA:p-T9-TIFA [cytosol] (Gallus gallus)
phospho-TIFA [cytosol] (Gallus gallus)
ALPK1:ADP-heptose:p-T9-TIFA:polyUb-TRAF6:p-T184,T187-TAK1:TAB1:TAB2/TAB3: free polyUb chain [cytosol] (Gallus gallus)
ALPK1:ADP-heptose:p-T9-TIFA oligomer:K63-linked pUb-TRAF6 oligomer [cytosol] (Gallus gallus)
ALPK1:ADP-heptose:p-T9-TIFA oligomer [cytosol] (Gallus gallus)
p-T9-TIFA:p-T9-TIFA [cytosol] (Gallus gallus)
phospho-TIFA [cytosol] (Gallus gallus)
Auto ubiquitination of TRAF6 bound to ALPK1:ADP-heptose:TIFA oligomer (Gallus gallus)
ALPK1:ADP-heptose:p-T9-TIFA oligomer:K63-linked pUb-TRAF6 oligomer [cytosol] (Gallus gallus)
ALPK1:ADP-heptose:p-T9-TIFA oligomer [cytosol] (Gallus gallus)
p-T9-TIFA:p-T9-TIFA [cytosol] (Gallus gallus)
phospho-TIFA [cytosol] (Gallus gallus)
ALPK1:ADP-heptose:p-T9-TIFA oligomer:TRAF6 oligomer [cytosol] (Gallus gallus)
ALPK1:ADP-heptose:p-T9-TIFA oligomer [cytosol] (Gallus gallus)
p-T9-TIFA:p-T9-TIFA [cytosol] (Gallus gallus)
phospho-TIFA [cytosol] (Gallus gallus)
TIFA oligomerization (Gallus gallus)
ALPK1:ADP-heptose:p-T9-TIFA dimer [cytosol] (Gallus gallus)
p-T9-TIFA:p-T9-TIFA [cytosol] (Gallus gallus)
phospho-TIFA [cytosol] (Gallus gallus)
ALPK1:ADP-heptose:p-T9-TIFA oligomer [cytosol] (Gallus gallus)
p-T9-TIFA:p-T9-TIFA [cytosol] (Gallus gallus)
phospho-TIFA [cytosol] (Gallus gallus)
TRAF6 oligomerizes within the ALPK1:ADP-heptose:TIFA oligomer complex (Gallus gallus)
ALPK1:ADP-heptose:p-T9-TIFA oligomer:TRAF6 [cytosol] (Gallus gallus)
ALPK1:ADP-heptose:p-T9-TIFA oligomer [cytosol] (Gallus gallus)
p-T9-TIFA:p-T9-TIFA [cytosol] (Gallus gallus)
phospho-TIFA [cytosol] (Gallus gallus)
ALPK1:ADP-heptose:p-T9-TIFA oligomer:TRAF6 oligomer [cytosol] (Gallus gallus)
ALPK1:ADP-heptose:p-T9-TIFA oligomer [cytosol] (Gallus gallus)
p-T9-TIFA:p-T9-TIFA [cytosol] (Gallus gallus)
phospho-TIFA [cytosol] (Gallus gallus)
External Reference Information
External Reference
UniProt:E1BXY0
Gene Names
TIFA
Reference Genes
BioGPS Gene:422692 TIFA
ENSEMBL:ENSGALG00000012076
ENSEMBL:ENSGALG00010004065.1 TIFA
Monarch:422692 TIFA
NCBI Gene:422692 TIFA
Reference Transcript
RefSeq:XM_420645.5 TIFA
Other Identifiers
422692
GO:0002376
GO:0002753
GO:0005515
GO:0005737
GO:0007249
GO:0023052
GO:0043123
GO:0045087
GO:0051260
GO:0065003
GO:0098542
GT_A_87_P095811
GgaAffx.7657.1.S1_at
Participates
as a component of
p-T9-TIFA:p-T9-TIFA [cytosol] (Gallus gallus)
Other forms of this molecule
TIFA [cytosol]
Inferred From
p-T9-TIFA [cytosol]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-threonine at 9 (in Homo sapiens)
Coordinate
9
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Cross References
RefSeq
XP_420645.2
OpenTargets
ENSG00000145365
Ensembl
ENSGALG00010004065
,
ENSGALT00010009442
,
ENSGALP00010005575
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