Reactome | RPS27L [cytosol]

RPS27L [cytosol]

Stable Identifier

R-GGA-8868849

Type

Protein [EntityWithAccessionedSequence]

Species

Gallus gallus

Compartment

cytosol

Synonyms

RPS27L, A0A3Q2TV39

Locations in the PathwayBrowser

Expand all

Metabolism of RNA (Gallus gallus)

- Nonsense-Mediated Decay (NMD) (Gallus gallus)
  - Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Gallus gallus)
    - SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Gallus gallus)
      - SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Gallus gallus)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Gallus gallus)
        
        80S ribosome [cytosol] (Gallus gallus)
        
        40S ribosomal complex [cytosol] (Gallus gallus)
        
        RPS27,RPS27L [cytosol] (Gallus gallus)
        
        RPS27L [cytosol] (Gallus gallus)
      - SMG1:UPF1:EJC:Translated mRNP [cytosol] (Gallus gallus)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Gallus gallus)
        
        80S ribosome [cytosol] (Gallus gallus)
        
        40S ribosomal complex [cytosol] (Gallus gallus)
        
        RPS27,RPS27L [cytosol] (Gallus gallus)
        
        RPS27L [cytosol] (Gallus gallus)
    - SMG6 hydrolyzes mRNA with premature termination codon (Gallus gallus)
      - Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Gallus gallus)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Gallus gallus)
        
        80S ribosome [cytosol] (Gallus gallus)
        
        40S ribosomal complex [cytosol] (Gallus gallus)
        
        RPS27,RPS27L [cytosol] (Gallus gallus)
        
        RPS27L [cytosol] (Gallus gallus)
  - Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) (Gallus gallus)
    - Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Gallus gallus)
      - Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Gallus gallus)
        
        80S ribosome [cytosol] (Gallus gallus)
        
        40S ribosomal complex [cytosol] (Gallus gallus)
        
        RPS27,RPS27L [cytosol] (Gallus gallus)
        
        RPS27L [cytosol] (Gallus gallus)
      - UPF1:eRF3 Complex on Translated mRNA [cytosol] (Gallus gallus)
        
        Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Gallus gallus)
        
        80S ribosome [cytosol] (Gallus gallus)
        
        40S ribosomal complex [cytosol] (Gallus gallus)
        
        RPS27,RPS27L [cytosol] (Gallus gallus)
        
        RPS27L [cytosol] (Gallus gallus)

External Reference Information

External Reference

UniProt:A0A3Q2TV39

Gene Names

RPS27L

Reference Genes

BioGPS Gene:415372 RPS27L

ENSEMBL:ENSGALG00000052612

ENSEMBL:ENSGALG00010024508.1 RPS27L

KEGG Gene (Gallus gallus):415372 RPS27L

Monarch:415372 RPS27L

NCBI Gene:415372 RPS27L

Reference Transcript

RefSeq:NM_001277460.1 RPS27L

Other Identifiers

415372

GO:0000028

GO:0000278

GO:0003723

GO:0003735

GO:0005198

GO:0005634

GO:0005829

GO:0005840

GO:0006412

GO:0006978

GO:0008494

GO:0008656

GO:0012501

GO:0022627

GO:0023052

GO:0031571

GO:0042254

GO:0042771

GO:0043226

GO:0045182

GO:0045727

GO:0046872

GO:0065003

GO:0098772

GO:1990904

GT_A_87_P147253

GT_Xhyb_Chicken_CN223244_2622

Gga.5571.1.S1_at

Participates

as a candidate of

RPS27,RPS27L [cytosol] (Gallus gallus)

Other forms of this molecule

RPS27L [nucleoplasm]

Inferred From

RPS27L [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_001264389.1

OpenTargets

ENSG00000185088

Ensembl

ENSGALG00010024508, ENSGALP00010036536, ENSGALT00010059776

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