Reactome | RPS16 [cytosol]

RPS16 [cytosol]

Stable Identifier

R-GGA-72337

Type

Protein [EntityWithAccessionedSequence]

Species

Gallus gallus

Compartment

cytosol

Synonyms

RPS16, R4GGJ0

Locations in the PathwayBrowser

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Metabolism of RNA (Gallus gallus)

- Nonsense-Mediated Decay (NMD) (Gallus gallus)
  - Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Gallus gallus)
    - SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Gallus gallus)
      - SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Gallus gallus)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Gallus gallus)
        
        80S ribosome [cytosol] (Gallus gallus)
        
        40S ribosomal complex [cytosol] (Gallus gallus)
        
        RPS16 [cytosol] (Gallus gallus)
      - SMG1:UPF1:EJC:Translated mRNP [cytosol] (Gallus gallus)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Gallus gallus)
        
        80S ribosome [cytosol] (Gallus gallus)
        
        40S ribosomal complex [cytosol] (Gallus gallus)
        
        RPS16 [cytosol] (Gallus gallus)
    - SMG6 hydrolyzes mRNA with premature termination codon (Gallus gallus)
      - Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Gallus gallus)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Gallus gallus)
        
        80S ribosome [cytosol] (Gallus gallus)
        
        40S ribosomal complex [cytosol] (Gallus gallus)
        
        RPS16 [cytosol] (Gallus gallus)
  - Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) (Gallus gallus)
    - Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Gallus gallus)
      - Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Gallus gallus)
        
        80S ribosome [cytosol] (Gallus gallus)
        
        40S ribosomal complex [cytosol] (Gallus gallus)
        
        RPS16 [cytosol] (Gallus gallus)
      - UPF1:eRF3 Complex on Translated mRNA [cytosol] (Gallus gallus)
        
        Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Gallus gallus)
        
        80S ribosome [cytosol] (Gallus gallus)
        
        40S ribosomal complex [cytosol] (Gallus gallus)
        
        RPS16 [cytosol] (Gallus gallus)

External Reference Information

External Reference

UniProt:R4GGJ0

Gene Names

RPS16

Reference Genes

BioGPS Gene:417871 RPS16

ENSEMBL:ENSGALG00000026490

ENSEMBL:ENSGALG00010013358.1 RPS16

KEGG Gene (Gallus gallus):417871 RPS16

Monarch:417871 RPS16

NCBI Gene:417871 RPS16

Reference Transcript

RefSeq:XM_416113.5 RPS16

Other Identifiers

417871

GO:0000462

GO:0003723

GO:0003735

GO:0005198

GO:0005634

GO:0005829

GO:0005840

GO:0006364

GO:0006412

GO:0022626

GO:0022627

GO:0032040

GO:0042254

GO:0042274

GO:0043226

GO:1990904

GT_A_87_P106598

GT_A_87_P238478

GT_A_87_P257273

GT_Xhyb_Chicken_CN220733_1847

Gga.4509.1.S1_at

Participates

as a component of

40S ribosomal complex [cytosol] (Gallus gallus)

Other forms of this molecule

RPS16 [nucleoplasm]

Inferred From

RPS16 [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_416113.1

OpenTargets

ENSG00000105193

Ensembl

ENSGALT00010032148, ENSGALP00010018938, ENSGALG00010013358

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