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FEN1 [nucleoplasm]
Stable Identifier
R-GGA-54745
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
nucleoplasm
Synonyms
Q5ZLN4
Locations in the PathwayBrowser
Expand all
DNA Repair (Gallus gallus)
DNA Double-Strand Break Repair (Gallus gallus)
Homology Directed Repair (Gallus gallus)
HDR through MMEJ (alt-NHEJ) (Gallus gallus)
FEN1 cleaves displaced ssDNA flaps during MMEJ (Gallus gallus)
Extended microhomologous 3'-ssDNA overhangs-flap-DSB:MRN:RBBP8:FEN1 [nucleoplasm] (Gallus gallus)
FEN1 [nucleoplasm] (Gallus gallus)
FEN1 [nucleoplasm] (Gallus gallus)
PARP1 or PARP2, FEN1 and POLQ are recruited to MMEJ site (Gallus gallus)
Annealed microhomologous 3'-ssDNA overhangs-DSB:MRN:RBBP8:PARP1,PARP2:FEN1:POLQ [nucleoplasm] (Gallus gallus)
FEN1 [nucleoplasm] (Gallus gallus)
FEN1 [nucleoplasm] (Gallus gallus)
PARP1,PARP2 dimers bound to MMEJ sites autoPARylate (Gallus gallus)
Extended microhomologous 3'-ssDNA overhangs-flap-DSB:MRN:RBBP8:FEN1 [nucleoplasm] (Gallus gallus)
FEN1 [nucleoplasm] (Gallus gallus)
Extended microhomologous 3'-ssDNA overhangs-flap-DSB:MRN:RBBP8:PARP1,PARP2:FEN1:POLQ [nucleoplasm] (Gallus gallus)
FEN1 [nucleoplasm] (Gallus gallus)
POLQ extends annealed 3'-ssDNA overhangs in MMEJ (Gallus gallus)
Annealed microhomologous 3'-ssDNA overhangs-DSB:MRN:RBBP8:PARP1,PARP2:FEN1:POLQ [nucleoplasm] (Gallus gallus)
FEN1 [nucleoplasm] (Gallus gallus)
Extended microhomologous 3'-ssDNA overhangs-flap-DSB:MRN:RBBP8:PARP1,PARP2:FEN1:POLQ [nucleoplasm] (Gallus gallus)
FEN1 [nucleoplasm] (Gallus gallus)
External Reference Information
External Reference
UniProt:Q5ZLN4
Reference Genes
BioGPS Gene:769677
ENSEMBL:ENSGALG00000033781
ENSEMBL:ENSGALG00000063786
ENSEMBL:ENSGALG00010021211.1
ENSEMBL:ENSGALG00015014693
KEGG Gene (Gallus gallus):769677
Monarch:769677
NCBI Gene:769677
Reference Transcript
RefSeq:NM_001079491.1
Other Identifiers
769677
GO:0000287
GO:0000781
GO:0003677
GO:0003824
GO:0004518
GO:0004519
GO:0004523
GO:0004527
GO:0005634
GO:0005654
GO:0005694
GO:0005730
GO:0005739
GO:0006260
GO:0006281
GO:0006284
GO:0006974
GO:0008409
GO:0016787
GO:0016788
GO:0017108
GO:0030145
GO:0032991
GO:0043137
GO:0043226
GO:0045876
GO:0046872
GO:0048256
GO:0090305
GO:0140097
GO:0140098
GT_A_87_P008425
GT_A_87_P036915
Gga.4353.1.S1_s_at
GgaAffx.2263.1.S1_at
Participates
as an output of
FEN1 cleaves displaced ssDNA flaps during MMEJ (Gallus gallus)
as an input of
PARP1 or PARP2, FEN1 and POLQ are recruited to MMEJ site (Gallus gallus)
as a component of
Annealed microhomologous 3'-ssDNA overhangs-DSB:MRN:RBBP8:PARP1,PARP2:FEN1:POLQ [nucleoplasm] (Gallus gallus)
Extended microhomologous 3'-ssDNA overhangs-flap-DSB:MRN:RBBP8:FEN1 [nucleoplasm] (Gallus gallus)
Extended microhomologous 3'-ssDNA overhangs-flap-DSB:MRN:RBBP8:PARP1,PARP2:FEN1:POLQ [nucleoplasm] (Gallus gallus)
Inferred From
FEN1 [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
NP_001072959.1
Ensembl
ENSGALG00010021211
,
ENSGALP00010030591
,
ENSGALT00010051395
,
ENSGALP00010030586
,
ENSGALT00010051400
PRO
Q5ZLN4
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