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phospho-p-Y31,Y118-PXN [cytosol]
Stable Identifier
R-GGA-5218693
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
cytosol
Synonyms
A0A1D5PGG4
Locations in the PathwayBrowser
Expand all
Signal Transduction (Gallus gallus)
Signaling by Non-Receptor Tyrosine Kinases (Gallus gallus)
Signaling by PTK6 (Gallus gallus)
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases (Gallus gallus)
Activation of RAC1 by the PXN:CRK complex (Gallus gallus)
p-Y31,Y118-PXN:CRK:DOCK180:ELMO1,ELMO2 [cytosol] (Gallus gallus)
phospho-p-Y31,Y118-PXN [cytosol] (Gallus gallus)
Phosphorylated PXN recruits the CRK complex (Gallus gallus)
p-Y31,Y118-PXN:CRK:DOCK180:ELMO1,ELMO2 [cytosol] (Gallus gallus)
phospho-p-Y31,Y118-PXN [cytosol] (Gallus gallus)
phospho-p-Y31,Y118-PXN [cytosol] (Gallus gallus)
Signaling by Receptor Tyrosine Kinases (Gallus gallus)
Signaling by VEGF (Gallus gallus)
VEGFA-VEGFR2 Pathway (Gallus gallus)
CRK binds BCAR1 and or PXN (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1,VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Gallus gallus)
phospho-p-Y31,Y118-PXN [cytosol] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1/p-Y31,Y118-PAX:CRK [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1,VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Gallus gallus)
phospho-p-Y31,Y118-PXN [cytosol] (Gallus gallus)
DOCK180:ELMO binds CRK (Gallus gallus)
CRK:DOCK180:ELMO1,ELMO2:VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1,VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1,VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Gallus gallus)
phospho-p-Y31,Y118-PXN [cytosol] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1/p-Y31,Y118-PAX:CRK [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1,VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Gallus gallus)
phospho-p-Y31,Y118-PXN [cytosol] (Gallus gallus)
DOCK180:ELMO exchanges GTP for GDP, activating RAC1 (Gallus gallus)
CRK:DOCK180:ELMO1,ELMO2:VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1,VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1,VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Gallus gallus)
phospho-p-Y31,Y118-PXN [cytosol] (Gallus gallus)
PTK2 and SRC-1 phosphorylate PXN on Y31 and Y118 (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Gallus gallus)
phospho-p-Y31,Y118-PXN [cytosol] (Gallus gallus)
External Reference Information
External Reference
UniProt:A0A1D5PGG4
Reference Genes
ENSEMBL:ENSGALG00000007247
Participates
as a component of
VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Gallus gallus)
p-Y31,Y118-PXN:CRK:DOCK180:ELMO1,ELMO2 [cytosol] (Gallus gallus)
as an input of
Phosphorylated PXN recruits the CRK complex (Gallus gallus)
Other forms of this molecule
phospho-p-Y-PXN [plasma membrane]
PXN [plasma membrane]
PXN [cytosol]
Inferred From
p-Y31,Y118-PXN [cytosol]
(Homo sapiens)
Modified Residues
Name
O4'-phospho-L-tyrosine at 31 (in Homo sapiens)
Coordinate
31
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 118 (in Homo sapiens)
Coordinate
118
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
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