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phospho-IRF-3 [nucleoplasm]
Stable Identifier
R-GGA-450270
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
nucleoplasm
Synonyms
p-S477,S479-IRF7, Q90ZD4
Locations in the PathwayBrowser
Expand all
Immune System (Gallus gallus)
Innate Immune System (Gallus gallus)
Cytosolic sensors of pathogen-associated DNA (Gallus gallus)
DEx/H-box helicases activate type I IFN and inflammatory cytokines production (Gallus gallus)
p-IRF7:p-IRF7 translocates to the nucleus (Gallus gallus)
2xp-S477,S479-IRF7 [nucleoplasm] (Gallus gallus)
phospho-IRF-3 [nucleoplasm] (Gallus gallus)
DDX58/IFIH1-mediated induction of interferon-alpha/beta (Gallus gallus)
TRAF6 mediated IRF7 activation (Gallus gallus)
Translocation of p-IRF7:p-IRF7 to nucleus (Gallus gallus)
2xp-S477,S479-IRF7 [nucleoplasm] (Gallus gallus)
phospho-IRF-3 [nucleoplasm] (Gallus gallus)
p-IRF7 dimer interacts with coactivator CBP/p300 (Gallus gallus)
2xp-S477,S479-IRF7 [nucleoplasm] (Gallus gallus)
phospho-IRF-3 [nucleoplasm] (Gallus gallus)
CBP/p300:pIRF7:pIRF7 [nucleoplasm] (Gallus gallus)
2xp-S477,S479-IRF7 [nucleoplasm] (Gallus gallus)
phospho-IRF-3 [nucleoplasm] (Gallus gallus)
Toll-like Receptor Cascades (Gallus gallus)
Toll Like Receptor 3 (TLR3) Cascade (Gallus gallus)
TICAM1-dependent activation of IRF3/IRF7 (Gallus gallus)
Dimerized phospho-IRF3/IRF7 is transported to the nucleus (Gallus gallus)
2xp-S477,S479-IRF7 [nucleoplasm] (Gallus gallus)
phospho-IRF-3 [nucleoplasm] (Gallus gallus)
Toll Like Receptor 4 (TLR4) Cascade (Gallus gallus)
MyD88-independent TLR4 cascade (Gallus gallus)
TRIF (TICAM1)-mediated TLR4 signaling (Gallus gallus)
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) (Gallus gallus)
Dimerized phospho-IRF3/IRF7 is transported to the nucleus (Gallus gallus)
2xp-S477,S479-IRF7 [nucleoplasm] (Gallus gallus)
phospho-IRF-3 [nucleoplasm] (Gallus gallus)
Toll Like Receptor 7/8 (TLR7/8) Cascade (Gallus gallus)
MyD88 dependent cascade initiated on endosome (Gallus gallus)
TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling (Gallus gallus)
Translocation of p-IRF7:p-IRF7 to nucleus (Gallus gallus)
2xp-S477,S479-IRF7 [nucleoplasm] (Gallus gallus)
phospho-IRF-3 [nucleoplasm] (Gallus gallus)
Toll Like Receptor 9 (TLR9) Cascade (Gallus gallus)
MyD88 dependent cascade initiated on endosome (Gallus gallus)
TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling (Gallus gallus)
Translocation of p-IRF7:p-IRF7 to nucleus (Gallus gallus)
2xp-S477,S479-IRF7 [nucleoplasm] (Gallus gallus)
phospho-IRF-3 [nucleoplasm] (Gallus gallus)
External Reference Information
External Reference
UniProt:Q90ZD4
Gene Names
IRF-3
Reference Genes
BioGPS Gene:396330 IRF-3
ENSEMBL:ENSGALG00000014297
ENSEMBL:ENSGALG00010023005.1 IRF-3
KEGG Gene (Gallus gallus):396330 IRF-3
Monarch:396330 IRF-3
NCBI Gene:396330 IRF-3
Reference Transcript
RefSeq:NM_205372.1 IRF-3
Other Identifiers
396330
GO:0000976
GO:0000978
GO:0000981
GO:0002376
GO:0003677
GO:0003700
GO:0005515
GO:0005634
GO:0006351
GO:0006355
GO:0006357
GO:0043226
GO:0045893
GO:0140110
GT_A_87_P053671
Gga.1087.1.S1_at
Participates
as a component of
2xp-S477,S479-IRF7 [nucleoplasm] (Gallus gallus)
Other forms of this molecule
phospho-IRF-3 [cytosol]
IRF-3 [cytosol]
Inferred From
p-S477,S479-IRF7 [nucleoplasm]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-serine at 477 (in Homo sapiens)
Coordinate
477
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 479 (in Homo sapiens)
Coordinate
479
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
RefSeq
NP_990703.1
Ensembl
ENSGALT00010056028
,
ENSGALP00010033902
,
ENSGALG00010023005
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