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gp130 [plasma membrane]
Stable Identifier
R-GGA-448453
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
plasma membrane
Synonyms
IL6ST, Q9W6U9
Locations in the PathwayBrowser
Expand all
Immune System (Gallus gallus)
Cytokine Signaling in Immune system (Gallus gallus)
Signaling by Interleukins (Gallus gallus)
Interleukin-12 family signaling (Gallus gallus)
Interleukin-35 Signalling (Gallus gallus)
JAK1/JAK2 bound to IL12RB2:IL6ST receptor phosphorylates STAT1 and STAT4 (Gallus gallus)
IL35:IL6ST:p-JAK1:IL12RB2:p-JAK2:STAT1:STAT4 [plasma membrane] (Gallus gallus)
STAT1:IL12A:EBI3:IL6ST:p-JAK1:IL12RB2:p-JAK2 [plasma membrane] (Gallus gallus)
IL35:IL6ST:p-JAK1:IL12RB2:p-JAK2 [plasma membrane] (Gallus gallus)
IL6ST:p-JAK1 [plasma membrane] (Gallus gallus)
gp130 [plasma membrane] (Gallus gallus)
IL35:IL6ST:p-JAK1:IL12RB2:p-JAK2:p-STAT1:p-STAT4 [plasma membrane] (Gallus gallus)
IL35:IL6ST:p-JAK1:IL12RB2:p-JAK2 [plasma membrane] (Gallus gallus)
IL6ST:p-JAK1 [plasma membrane] (Gallus gallus)
gp130 [plasma membrane] (Gallus gallus)
JAK1/JAK2 bound to IL35:IL6ST:IL12RB2 receptor are phosphorylated (Gallus gallus)
IL35:IL6ST:JAK1:IL12RB2:JAK2 [plasma membrane] (Gallus gallus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Gallus gallus)
gp130 [plasma membrane] (Gallus gallus)
IL35:IL6ST:p-JAK1:IL12RB2:p-JAK2 [plasma membrane] (Gallus gallus)
IL6ST:p-JAK1 [plasma membrane] (Gallus gallus)
gp130 [plasma membrane] (Gallus gallus)
JAK1/JAK2/TYK2 bound to IL6ST:IL6ST are phosphorylated (Gallus gallus)
IL-35:(IL6ST:JAK1:JAK2) dimer [plasma membrane] (Gallus gallus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Gallus gallus)
gp130 [plasma membrane] (Gallus gallus)
IL35:(IL6ST:p-JAK1:p-JAK2:p-TYK2) dimer [plasma membrane] (Gallus gallus)
IL6ST:p-JAK1:p-JAK2:p-TYK2 [plasma membrane] (Gallus gallus)
gp130 [plasma membrane] (Gallus gallus)
JAK1/JAK2/TYK2 bound to IL6ST:IL6ST phosphorylate STAT1 (Gallus gallus)
IL-35:(IL6ST:p-JAK1:p-JAK2) dimer: STAT1 [plasma membrane] (Gallus gallus)
IL-35:(IL6ST:p-JAK1:p-JAK2) dimer [plasma membrane] (Gallus gallus)
gp130 [plasma membrane] (Gallus gallus)
IL-35:(IL6ST:p-JAK1:p-JAK2) dimer:p-STAT1 [plasma membrane] (Gallus gallus)
IL-35:(IL6ST:p-JAK1:p-JAK2) dimer [plasma membrane] (Gallus gallus)
gp130 [plasma membrane] (Gallus gallus)
STAT1 and STAT4 associate with IL12RB2:IL6ST receptor (Gallus gallus)
IL35:IL6ST:p-JAK1:IL12RB2:p-JAK2 [plasma membrane] (Gallus gallus)
IL6ST:p-JAK1 [plasma membrane] (Gallus gallus)
gp130 [plasma membrane] (Gallus gallus)
IL35:IL6ST:p-JAK1:IL12RB2:p-JAK2:STAT1:STAT4 [plasma membrane] (Gallus gallus)
STAT1:IL12A:EBI3:IL6ST:p-JAK1:IL12RB2:p-JAK2 [plasma membrane] (Gallus gallus)
IL35:IL6ST:p-JAK1:IL12RB2:p-JAK2 [plasma membrane] (Gallus gallus)
IL6ST:p-JAK1 [plasma membrane] (Gallus gallus)
gp130 [plasma membrane] (Gallus gallus)
STAT1 associates with IL6ST:IL6ST (Gallus gallus)
IL-35:(IL6ST:p-JAK1:p-JAK2) dimer [plasma membrane] (Gallus gallus)
gp130 [plasma membrane] (Gallus gallus)
IL-35:(IL6ST:p-JAK1:p-JAK2) dimer: STAT1 [plasma membrane] (Gallus gallus)
IL-35:(IL6ST:p-JAK1:p-JAK2) dimer [plasma membrane] (Gallus gallus)
gp130 [plasma membrane] (Gallus gallus)
p-STAT1 and p-STAT4 dissociate from IL12RB2:IL6ST receptor (Gallus gallus)
IL35:IL6ST:p-JAK1:IL12RB2:p-JAK2 [plasma membrane] (Gallus gallus)
IL6ST:p-JAK1 [plasma membrane] (Gallus gallus)
gp130 [plasma membrane] (Gallus gallus)
IL35:IL6ST:p-JAK1:IL12RB2:p-JAK2:p-STAT1:p-STAT4 [plasma membrane] (Gallus gallus)
IL35:IL6ST:p-JAK1:IL12RB2:p-JAK2 [plasma membrane] (Gallus gallus)
IL6ST:p-JAK1 [plasma membrane] (Gallus gallus)
gp130 [plasma membrane] (Gallus gallus)
p-STAT1 dissociates from IL6ST:IL6ST (Gallus gallus)
IL-35:(IL6ST:p-JAK1:p-JAK2) dimer [plasma membrane] (Gallus gallus)
gp130 [plasma membrane] (Gallus gallus)
IL-35:(IL6ST:p-JAK1:p-JAK2) dimer:p-STAT1 [plasma membrane] (Gallus gallus)
IL-35:(IL6ST:p-JAK1:p-JAK2) dimer [plasma membrane] (Gallus gallus)
gp130 [plasma membrane] (Gallus gallus)
Interleukin-6 family signaling (Gallus gallus)
IL-6-type cytokine receptor ligand interactions (Gallus gallus)
IL11:IL11RA binds IL6ST:JAK1,JAK2,(TYK2) (Gallus gallus)
IL6RA:IL6:IL6RB:JAKs [plasma membrane] (Gallus gallus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Gallus gallus)
gp130 [plasma membrane] (Gallus gallus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Gallus gallus)
gp130 [plasma membrane] (Gallus gallus)
LIFR:JAKs bind gp130:JAKs:CNTFR (Gallus gallus)
CNTF:CNTFR,CRLF1:CLCF1:CNTFR:IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Gallus gallus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Gallus gallus)
gp130 [plasma membrane] (Gallus gallus)
CNTF:CNTFR,CRLF1:CLCF1:CNTFR:gp130:JAKs:LIFR:JAKs [plasma membrane] (Gallus gallus)
CNTF:CNTFR,CRLF1:CLCF1:CNTFR:IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Gallus gallus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Gallus gallus)
gp130 [plasma membrane] (Gallus gallus)
Interleukin-6 signaling (Gallus gallus)
Assembly of hexameric IL-6 receptor (Gallus gallus)
IL6 receptor hexamer:JAKs [plasma membrane] (Gallus gallus)
IL6 receptor trimer:JAKs [plasma membrane] (Gallus gallus)
IL6:IL6RA:IL6RB:JAKs [plasma membrane] (Gallus gallus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Gallus gallus)
gp130 [plasma membrane] (Gallus gallus)
IL6:sIL6R:IL6RB:JAKs [plasma membrane] (Gallus gallus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Gallus gallus)
gp130 [plasma membrane] (Gallus gallus)
IL6 receptor trimer:JAKs [plasma membrane] (Gallus gallus)
IL6:IL6RA:IL6RB:JAKs [plasma membrane] (Gallus gallus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Gallus gallus)
gp130 [plasma membrane] (Gallus gallus)
IL6:sIL6R:IL6RB:JAKs [plasma membrane] (Gallus gallus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Gallus gallus)
gp130 [plasma membrane] (Gallus gallus)
IL6:IL6R binds IL6ST:JAK1,JAK2,(TYK2) (Gallus gallus)
IL6:IL6RA:IL6RB:JAKs [plasma membrane] (Gallus gallus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Gallus gallus)
gp130 [plasma membrane] (Gallus gallus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Gallus gallus)
gp130 [plasma membrane] (Gallus gallus)
IL6:IL6R-2 binds IL6ST:JAK1, JAK2, (TYK2) (Gallus gallus)
IL6:sIL6R:IL6RB:JAKs [plasma membrane] (Gallus gallus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Gallus gallus)
gp130 [plasma membrane] (Gallus gallus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Gallus gallus)
gp130 [plasma membrane] (Gallus gallus)
IL6ST is tyrosine phosphorylated (Gallus gallus)
IL6 receptor hexamer:Activated JAKs [plasma membrane] (Gallus gallus)
IL6 receptor trimer:Activated JAKs [plasma membrane] (Gallus gallus)
IL6:IL6RA:IL6RB:Activated JAKs [plasma membrane] (Gallus gallus)
IL6RB:Activated JAKs [plasma membrane] (Gallus gallus)
gp130 [plasma membrane] (Gallus gallus)
IL6:sIL6R:IL6RB:Activated JAKs [plasma membrane] (Gallus gallus)
IL6RB:Activated JAKs [plasma membrane] (Gallus gallus)
gp130 [plasma membrane] (Gallus gallus)
JAK activation (Gallus gallus)
IL6 receptor hexamer:Activated JAKs [plasma membrane] (Gallus gallus)
IL6 receptor trimer:Activated JAKs [plasma membrane] (Gallus gallus)
IL6:IL6RA:IL6RB:Activated JAKs [plasma membrane] (Gallus gallus)
IL6RB:Activated JAKs [plasma membrane] (Gallus gallus)
gp130 [plasma membrane] (Gallus gallus)
IL6:sIL6R:IL6RB:Activated JAKs [plasma membrane] (Gallus gallus)
IL6RB:Activated JAKs [plasma membrane] (Gallus gallus)
gp130 [plasma membrane] (Gallus gallus)
IL6 receptor hexamer:JAKs [plasma membrane] (Gallus gallus)
IL6 receptor trimer:JAKs [plasma membrane] (Gallus gallus)
IL6:IL6RA:IL6RB:JAKs [plasma membrane] (Gallus gallus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Gallus gallus)
gp130 [plasma membrane] (Gallus gallus)
IL6:sIL6R:IL6RB:JAKs [plasma membrane] (Gallus gallus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Gallus gallus)
gp130 [plasma membrane] (Gallus gallus)
External Reference Information
External Reference
UniProt:Q9W6U9
Gene Names
gp130
Reference Genes
BioGPS Gene:395684 gp130
ENSEMBL:ENSGALG00000014716
ENSEMBL:ENSGALG00010012930.1 gp130
KEGG Gene (Gallus gallus):395684 gp130
Monarch:395684 gp130
NCBI Gene:395684 gp130
Reference Transcript
RefSeq:XM_015277242.1 gp130
RefSeq:NM_204871.1 gp130
Other Identifiers
395684
GO:0004896
GO:0004915
GO:0005515
GO:0005886
GO:0009897
GO:0016020
GO:0019221
GO:0019955
GO:0019981
GO:0023052
GO:0043235
GO:0060089
GO:0070102
GT_A_87_P015927
GT_A_87_P037522
Gga.2225.1.S1_at
Gga.7731.1.S1_at
Participates
as a component of
IL6ST:p-JAK1:p-JAK2:p-TYK2 [plasma membrane] (Gallus gallus)
IL-35:(IL6ST:p-JAK1:p-JAK2) dimer [plasma membrane] (Gallus gallus)
IL6ST:p-JAK1 [plasma membrane] (Gallus gallus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Gallus gallus)
IL6RB:Activated JAKs [plasma membrane] (Gallus gallus)
Other forms of this molecule
gp130 [extracellular region]
phospho-gp130 [plasma membrane]
Inferred From
IL6ST [plasma membrane]
(Homo sapiens)
Cross References
RefSeq
XP_015132728.1
,
NP_990202.1
Ensembl
ENSGALP00010018050
,
ENSGALG00010012930
,
ENSGALT00010031050
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