Cis-heterodimerization of NgCAM and Contactin-1/F3/F11

Stable Identifier
R-GGA-443776
Type
Reaction [binding]
Species
Gallus gallus
Compartment
plasma membrane
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Cis-heterodimerization of NgCAM and Contactin-1/F3/F11
By analogy to the well-studied chicken system, L1 heterophilically binds to F3/F11/Contactin-1 in cis manner via an L1-binding site resides in the first two immunoglobulin-like domains of Contactin-1.
Literature References
PubMed ID Title Journal Year
7682821 The axonal recognition molecule F11 is a multifunctional protein: specific domains mediate interactions with Ng-CAM and restrictin

Hubert, M, Tarnok, A, Rathjen, FG, Brummendorf, T, Leuschner, R, Treubert, U

Neuron 1993
Participants
Input
Output
Orthologous Events
Cis-heterodimerization of L1 and Contactin-1/F3/F11 (Homo sapiens)
Authored
Garapati, P V  (2008-07-30)
Reviewed
Maness, PF  (2010-02-16)
Created
Garapati, P V  (2009-10-12)
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