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phospho-PAK1 [cytosol]
Stable Identifier
R-GGA-399819
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
cytosol
Synonyms
p-S144,T423-PAK1, E1C3P6
Locations in the PathwayBrowser
Expand all
Developmental Biology (Gallus gallus)
Nervous system development (Gallus gallus)
Axon guidance (Gallus gallus)
L1CAM interactions (Gallus gallus)
Signal transduction by L1 (Gallus gallus)
Interaction of PAK1 with Rac1-GTP (Gallus gallus)
pPAK1:Rac1-GTP [cytosol] (Gallus gallus)
phospho-PAK1 [cytosol] (Gallus gallus)
Semaphorin interactions (Gallus gallus)
Sema3A PAK dependent Axon repulsion (Gallus gallus)
Autophosphorylation of PAK (Gallus gallus)
Sema3A:Nrp-1:PlexinA:Rac1-GTP:pPAK [plasma membrane] (Gallus gallus)
p-S,T-PAK1,2,3 [cytosol] (Gallus gallus)
phospho-PAK1 [cytosol] (Gallus gallus)
Phosphorylation of LIMK-1 by PAK (Gallus gallus)
Sema3A:Nrp-1:PlexinA:Rac1-GTP:pPAK [plasma membrane] (Gallus gallus)
p-S,T-PAK1,2,3 [cytosol] (Gallus gallus)
phospho-PAK1 [cytosol] (Gallus gallus)
p-S,T-PAK1,2,3 [cytosol] (Gallus gallus)
phospho-PAK1 [cytosol] (Gallus gallus)
Immune System (Gallus gallus)
Innate Immune System (Gallus gallus)
Fc epsilon receptor (FCERI) signaling (Gallus gallus)
FCERI mediated MAPK activation (Gallus gallus)
Autophosphorylation of PAK (Gallus gallus)
p-2Y-PAK [cytosol] (Gallus gallus)
phospho-PAK1 [cytosol] (Gallus gallus)
Fcgamma receptor (FCGR) dependent phagocytosis (Gallus gallus)
Regulation of actin dynamics for phagocytic cup formation (Gallus gallus)
Autophosphorylation of PAK1 (Gallus gallus)
phospho-PAK1 [cytosol] (Gallus gallus)
PAK1 phosphorylates LIMK1 (Gallus gallus)
phospho-PAK1 [cytosol] (Gallus gallus)
Muscle contraction (Gallus gallus)
Smooth Muscle Contraction (Gallus gallus)
MYLK (MLCK) Active Calmodulin Binding (Gallus gallus)
p-S,T-PAK1,2 [cytosol] (Gallus gallus)
phospho-PAK1 [cytosol] (Gallus gallus)
Signal Transduction (Gallus gallus)
MAPK family signaling cascades (Gallus gallus)
MAPK6/MAPK4 signaling (Gallus gallus)
Autophosphorylation of PAK1,2,3 (Gallus gallus)
p-S,T-PAK1,2,3 [cytosol] (Gallus gallus)
phospho-PAK1 [cytosol] (Gallus gallus)
PAK1,2,3 phosphorylates MAPK6,4 (Gallus gallus)
p-S,T-PAK1,2,3 [cytosol] (Gallus gallus)
phospho-PAK1 [cytosol] (Gallus gallus)
Signaling by Receptor Tyrosine Kinases (Gallus gallus)
Signaling by VEGF (Gallus gallus)
VEGFA-VEGFR2 Pathway (Gallus gallus)
VEGFR2 mediated vascular permeability (Gallus gallus)
PAK1-3 autophosphorylates (Gallus gallus)
p-S,T-PAK1,2,3 [cytosol] (Gallus gallus)
phospho-PAK1 [cytosol] (Gallus gallus)
PAK1-3 phosphorylates VE-cadherin (Gallus gallus)
p-S,T-PAK1,2,3 [cytosol] (Gallus gallus)
phospho-PAK1 [cytosol] (Gallus gallus)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Gallus gallus)
Signaling by Rho GTPases (Gallus gallus)
RHO GTPase Effectors (Gallus gallus)
RHO GTPases activate PAKs (Gallus gallus)
Autophosphorylation of PAK1,2,3 (Gallus gallus)
p-S,T-PAK1,2,3 [cytosol] (Gallus gallus)
phospho-PAK1 [cytosol] (Gallus gallus)
MYLK (MLCK) Active Calmodulin Binding (Gallus gallus)
p-S,T-PAK1,2 [cytosol] (Gallus gallus)
phospho-PAK1 [cytosol] (Gallus gallus)
PAK1 or PAK2 phosphorylates MYLK (Gallus gallus)
p-S,T-PAK1,2 [cytosol] (Gallus gallus)
phospho-PAK1 [cytosol] (Gallus gallus)
PAK1 phosphorylates LIMK1 (Gallus gallus)
phospho-PAK1 [cytosol] (Gallus gallus)
PAK1 phosphorylates myosin phosphatase (Gallus gallus)
phospho-PAK1 [cytosol] (Gallus gallus)
External Reference Information
External Reference
UniProt:E1C3P6
Gene Names
PAK1
Reference Genes
BioGPS Gene:419083 PAK1
ENSEMBL:ENSGALG00000000681
ENSEMBL:ENSGALG00010002102.1 PAK1
KEGG Gene (Gallus gallus):419083 PAK1
Monarch:419083 PAK1
NCBI Gene:419083 PAK1
Reference Transcript
RefSeq:XM_015280855.1 PAK1
RefSeq:XM_015280856.1 PAK1
RefSeq:NM_001162372.3 PAK1
RefSeq:XM_015280854.1 PAK1
RefSeq:XM_015280853.1 PAK1
Other Identifiers
419083
GO:0000166
GO:0001726
GO:0001934
GO:0003824
GO:0004672
GO:0004674
GO:0005518
GO:0005524
GO:0005634
GO:0005654
GO:0005737
GO:0005829
GO:0005856
GO:0005884
GO:0005886
GO:0005911
GO:0006325
GO:0006338
GO:0006468
GO:0006974
GO:0007010
GO:0008092
GO:0008284
GO:0016310
GO:0016477
GO:0016740
GO:0023052
GO:0030036
GO:0030154
GO:0030335
GO:0031116
GO:0031267
GO:0032956
GO:0032991
GO:0033138
GO:0033148
GO:0035556
GO:0036211
GO:0042060
GO:0043015
GO:0043226
GO:0043408
GO:0048012
GO:0048754
GO:0048856
GO:0048870
GO:0050770
GO:0051179
GO:0051496
GO:0060244
GO:0065003
GO:0090063
GO:0140096
GO:1903608
GT_A_87_P023730
GT_A_87_P058676
GT_A_87_P111883
Gga.10881.1.S1_s_at
GgaAffx.26684.1.S1_at
Participates
as a component of
pPAK1:Rac1-GTP [cytosol] (Gallus gallus)
as a member of
p-S,T-PAK1,2,3 [cytosol] (Gallus gallus)
p-2Y-PAK [cytosol] (Gallus gallus)
as an output of
Autophosphorylation of PAK1 (Gallus gallus)
as a candidate of
p-S,T-PAK1,2 [cytosol] (Gallus gallus)
Other forms of this molecule
PAK1 [plasma membrane]
phospho-PAK1 [plasma membrane]
PAK1 [cytosol]
Inferred From
p-S144,T423-PAK1 [cytosol]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-serine at 144 (in Homo sapiens)
Coordinate
144
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-threonine at 423 (in Homo sapiens)
Coordinate
423
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Cross References
RefSeq
XP_015136342.1
,
XP_015136340.1
,
XP_015136341.1
,
NP_001155844.1
,
XP_015136339.1
OpenTargets
ENSG00000149269
Ensembl
ENSGALP00010002842
,
ENSGALT00010004716
,
ENSGALG00010002102
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