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activated TLR4:TRIF:RIP1:FADD:pro-caspase-8 [endosome membrane]
Stable Identifier
R-GGA-2562542
Type
Complex
Species
Gallus gallus
Compartment
endosome membrane
Locations in the PathwayBrowser
Expand all
Immune System (Gallus gallus)
Innate Immune System (Gallus gallus)
Toll-like Receptor Cascades (Gallus gallus)
Toll Like Receptor 4 (TLR4) Cascade (Gallus gallus)
MyD88-independent TLR4 cascade (Gallus gallus)
TRIF (TICAM1)-mediated TLR4 signaling (Gallus gallus)
TRIF-mediated programmed cell death (Gallus gallus)
Caspase-8 processing within TLR4 complex (Gallus gallus)
activated TLR4:TRIF:RIP1:FADD:pro-caspase-8 [endosome membrane] (Gallus gallus)
TLR4-induced ripoptosome assembly (Gallus gallus)
activated TLR4:TRIF:RIP1:FADD:pro-caspase-8 [endosome membrane] (Gallus gallus)
Programmed Cell Death (Gallus gallus)
Apoptosis (Gallus gallus)
Caspase activation via extrinsic apoptotic signalling pathway (Gallus gallus)
Caspase activation via Death Receptors in the presence of ligand (Gallus gallus)
Caspase-8 processing within TLR4 complex (Gallus gallus)
activated TLR4:TRIF:RIP1:FADD:pro-caspase-8 [endosome membrane] (Gallus gallus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
x 2
CASP8(1-479) [cytosol]
(Gallus gallus)
x 2
FADD [cytosol]
(Gallus gallus)
x 2
RIPK1 [cytosol]
(Gallus gallus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane]
(Gallus gallus)
Participates
as an input of
Caspase-8 processing within TLR4 complex (Gallus gallus)
as an output of
TLR4-induced ripoptosome assembly (Gallus gallus)
Inferred From
activated TLR4:TRIF:RIP1:FADD:pro-caspase-8 [endosome membrane]
(Homo sapiens)
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