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PAK2 [cytosol]
Stable Identifier
R-GGA-211604
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
cytosol
Synonyms
PAK2, E1BS97
Locations in the PathwayBrowser
Expand all
Developmental Biology (Gallus gallus)
Nervous system development (Gallus gallus)
Axon guidance (Gallus gallus)
EPH-Ephrin signaling (Gallus gallus)
Ephrin signaling (Gallus gallus)
PAK binds RAC and bPIX (Gallus gallus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:PAK1,3 [plasma membrane] (Gallus gallus)
PAK1/3, 2 [cytosol] (Gallus gallus)
PAK2 [cytosol] (Gallus gallus)
PAK1/3, 2 [cytosol] (Gallus gallus)
PAK2 [cytosol] (Gallus gallus)
PAKs autophosphorylate (Gallus gallus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:PAK1,3 [plasma membrane] (Gallus gallus)
PAK1/3, 2 [cytosol] (Gallus gallus)
PAK2 [cytosol] (Gallus gallus)
PAK1/3, 2 [cytosol] (Gallus gallus)
PAK2 [cytosol] (Gallus gallus)
Semaphorin interactions (Gallus gallus)
Sema3A PAK dependent Axon repulsion (Gallus gallus)
Activation of PAK by Rac1 (Gallus gallus)
PAK1,2,3 [cytosol] (Gallus gallus)
PAK2 [cytosol] (Gallus gallus)
PAK1,2,3 dimer [cytosol] (Gallus gallus)
PAK2 dimer [cytosol] (Gallus gallus)
PAK2 [cytosol] (Gallus gallus)
Sema3A:Nrp-1:PlexinA:Rac1-GTP:PAK [plasma membrane] (Gallus gallus)
PAK1,2,3 [cytosol] (Gallus gallus)
PAK2 [cytosol] (Gallus gallus)
Autophosphorylation of PAK (Gallus gallus)
PAK1,2,3 [cytosol] (Gallus gallus)
PAK2 [cytosol] (Gallus gallus)
Sema3A:Nrp-1:PlexinA:Rac1-GTP:PAK [plasma membrane] (Gallus gallus)
PAK1,2,3 [cytosol] (Gallus gallus)
PAK2 [cytosol] (Gallus gallus)
Immune System (Gallus gallus)
Adaptive Immune System (Gallus gallus)
Costimulation by the CD28 family (Gallus gallus)
CD28 co-stimulation (Gallus gallus)
CD28 dependent Vav1 pathway (Gallus gallus)
Activation of PAKs by RAC1 and CDC42 (Gallus gallus)
PAK1,2,3 [cytosol] (Gallus gallus)
PAK2 [cytosol] (Gallus gallus)
PAK1,2,3 dimer [cytosol] (Gallus gallus)
PAK2 dimer [cytosol] (Gallus gallus)
PAK2 [cytosol] (Gallus gallus)
PAK1,2,3:CDC42:GTP, RAC1:GTP [plasma membrane] (Gallus gallus)
PAK1,2,3 [cytosol] (Gallus gallus)
PAK2 [cytosol] (Gallus gallus)
Innate Immune System (Gallus gallus)
C-type lectin receptors (CLRs) (Gallus gallus)
CD209 (DC-SIGN) signaling (Gallus gallus)
PAK phosphorylates p21 RAF1 on S338 (Gallus gallus)
PAK1,2,3 [cytosol] (Gallus gallus)
PAK2 [cytosol] (Gallus gallus)
Fc epsilon receptor (FCERI) signaling (Gallus gallus)
FCERI mediated MAPK activation (Gallus gallus)
Autophosphorylation of PAK (Gallus gallus)
PAK dimer [cytosol] (Gallus gallus)
PAK2 dimer [cytosol] (Gallus gallus)
PAK2 [cytosol] (Gallus gallus)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP:PAK dimer [plasma membrane] (Gallus gallus)
PAK dimer [cytosol] (Gallus gallus)
PAK2 dimer [cytosol] (Gallus gallus)
PAK2 [cytosol] (Gallus gallus)
Recruitment of PAK to the membrane by binding active RAC1 (Gallus gallus)
PAK dimer [cytosol] (Gallus gallus)
PAK2 dimer [cytosol] (Gallus gallus)
PAK2 [cytosol] (Gallus gallus)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP:PAK dimer [plasma membrane] (Gallus gallus)
PAK dimer [cytosol] (Gallus gallus)
PAK2 dimer [cytosol] (Gallus gallus)
PAK2 [cytosol] (Gallus gallus)
Signal Transduction (Gallus gallus)
MAPK family signaling cascades (Gallus gallus)
MAPK6/MAPK4 signaling (Gallus gallus)
Activation of PAKs by RAC1 and CDC42 (Gallus gallus)
PAK1,2,3 [cytosol] (Gallus gallus)
PAK2 [cytosol] (Gallus gallus)
PAK1,2,3 dimer [cytosol] (Gallus gallus)
PAK2 dimer [cytosol] (Gallus gallus)
PAK2 [cytosol] (Gallus gallus)
PAK1,2,3:CDC42:GTP, RAC1:GTP [plasma membrane] (Gallus gallus)
PAK1,2,3 [cytosol] (Gallus gallus)
PAK2 [cytosol] (Gallus gallus)
Autophosphorylation of PAK1,2,3 (Gallus gallus)
CDC42:GTP,RAC1:GTP:PAK1,PAK2,PAK3 [plasma membrane] (Gallus gallus)
CDC42:GTP,RAC1:GTP:PAK2 [plasma membrane] (Gallus gallus)
PAK2 [cytosol] (Gallus gallus)
Signaling by Receptor Tyrosine Kinases (Gallus gallus)
Signaling by VEGF (Gallus gallus)
VEGFA-VEGFR2 Pathway (Gallus gallus)
CDC42:GTP binds PAK2 (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2:p-S21,Y420-FYN:PAK2 [plasma membrane] (Gallus gallus)
PAK2 dimer [cytosol] (Gallus gallus)
PAK2 [cytosol] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:NCK:p-S21,Y420-FYN:PAK2:CDC42:GTP [plasma membrane] (Gallus gallus)
PAK2 dimer:CDC42:GTP [plasma membrane] (Gallus gallus)
PAK2 dimer [cytosol] (Gallus gallus)
PAK2 [cytosol] (Gallus gallus)
PAK2 autophorylates (Gallus gallus)
PAK2 [cytosol] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:NCK:p-S21,Y420-FYN:PAK2:CDC42:GTP [plasma membrane] (Gallus gallus)
PAK2 dimer:CDC42:GTP [plasma membrane] (Gallus gallus)
PAK2 dimer [cytosol] (Gallus gallus)
PAK2 [cytosol] (Gallus gallus)
PAK2 binds NCK (Gallus gallus)
PAK2 dimer [cytosol] (Gallus gallus)
PAK2 [cytosol] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2:p-S21,Y420-FYN:PAK2 [plasma membrane] (Gallus gallus)
PAK2 dimer [cytosol] (Gallus gallus)
PAK2 [cytosol] (Gallus gallus)
VEGFR2 mediated vascular permeability (Gallus gallus)
PAK1-3 autophosphorylates (Gallus gallus)
PAK1,2,3 dimer [cytosol] (Gallus gallus)
PAK2 dimer [cytosol] (Gallus gallus)
PAK2 [cytosol] (Gallus gallus)
p-VAV family:PIP3:RAC1:GTP:PAK 1-3 [plasma membrane] (Gallus gallus)
PAK1,2,3 [cytosol] (Gallus gallus)
PAK2 [cytosol] (Gallus gallus)
PAK1-3 dimer disassociates (Gallus gallus)
2 x p-VAV family:PIP3:RAC1:GTP:PAK 1-3 [plasma membrane] (Gallus gallus)
PAK1,2,3 dimer [cytosol] (Gallus gallus)
PAK2 dimer [cytosol] (Gallus gallus)
PAK2 [cytosol] (Gallus gallus)
p-VAV family:PIP3:RAC1:GTP:PAK 1-3 [plasma membrane] (Gallus gallus)
PAK1,2,3 [cytosol] (Gallus gallus)
PAK2 [cytosol] (Gallus gallus)
RAC1 binds PAK1-3 (Gallus gallus)
2 x p-VAV family:PIP3:RAC1:GTP:PAK 1-3 [plasma membrane] (Gallus gallus)
PAK1,2,3 dimer [cytosol] (Gallus gallus)
PAK2 dimer [cytosol] (Gallus gallus)
PAK2 [cytosol] (Gallus gallus)
PAK1,2,3 dimer [cytosol] (Gallus gallus)
PAK2 dimer [cytosol] (Gallus gallus)
PAK2 [cytosol] (Gallus gallus)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Gallus gallus)
Signaling by Rho GTPases (Gallus gallus)
RHO GTPase Effectors (Gallus gallus)
RHO GTPases activate PAKs (Gallus gallus)
Autophosphorylation of PAK1,2,3 (Gallus gallus)
CDC42:GTP,RAC1:GTP:PAK1,PAK2,PAK3 [plasma membrane] (Gallus gallus)
CDC42:GTP,RAC1:GTP:PAK2 [plasma membrane] (Gallus gallus)
PAK2 [cytosol] (Gallus gallus)
RAC1 and CDC42 activate PAK2 (Gallus gallus)
CDC42:GTP,RAC1:GTP:PAK2 [plasma membrane] (Gallus gallus)
PAK2 [cytosol] (Gallus gallus)
PAK2 [cytosol] (Gallus gallus)
PAK2 dimer [cytosol] (Gallus gallus)
PAK2 [cytosol] (Gallus gallus)
RHO GTPase cycle (Gallus gallus)
RAC1 GTPase cycle (Gallus gallus)
RAC1 binds effectors at the plasma membrane (Gallus gallus)
RAC1 effectors [cytosol] (Gallus gallus)
PAK2 dimer [cytosol] (Gallus gallus)
PAK2 [cytosol] (Gallus gallus)
RAC1:GTP:RAC1 effectors [plasma membrane] (Gallus gallus)
RAC1 effectors [cytosol] (Gallus gallus)
PAK2 dimer [cytosol] (Gallus gallus)
PAK2 [cytosol] (Gallus gallus)
RAC2 GTPase cycle (Gallus gallus)
RAC2 binds effectors at the plasma membrane (Gallus gallus)
RAC2 plasma membrane effectors [cytosol] (Gallus gallus)
PAK2 dimer [cytosol] (Gallus gallus)
PAK2 [cytosol] (Gallus gallus)
RAC2:GTP:RAC2 cytosolic effectors [plasma membrane] (Gallus gallus)
RAC2 plasma membrane effectors [cytosol] (Gallus gallus)
PAK2 dimer [cytosol] (Gallus gallus)
PAK2 [cytosol] (Gallus gallus)
RAC3 GTPase cycle (Gallus gallus)
RAC3 binds effectors at the plasma membrane (Gallus gallus)
RAC3 effectors [cytosol] (Gallus gallus)
PAK2 dimer [cytosol] (Gallus gallus)
PAK2 [cytosol] (Gallus gallus)
RAC3:GTP:RAC3 effectors [plasma membrane] (Gallus gallus)
RAC3 effectors [cytosol] (Gallus gallus)
PAK2 dimer [cytosol] (Gallus gallus)
PAK2 [cytosol] (Gallus gallus)
RHOG GTPase cycle (Gallus gallus)
RHOG binds effectors at the plasma membrane (Gallus gallus)
RHOG plasma membrane effectors [cytosol] (Gallus gallus)
PAK2 dimer [cytosol] (Gallus gallus)
PAK2 [cytosol] (Gallus gallus)
RHOG:GTP:RHOG plasma membrane effectors [plasma membrane] (Gallus gallus)
RHOG plasma membrane effectors [cytosol] (Gallus gallus)
PAK2 dimer [cytosol] (Gallus gallus)
PAK2 [cytosol] (Gallus gallus)
RHOH GTPase cycle (Gallus gallus)
RHOH binds effectors at the plasma membrane (Gallus gallus)
RHOH effectors [cytosol] (Gallus gallus)
PAK2 dimer [cytosol] (Gallus gallus)
PAK2 [cytosol] (Gallus gallus)
RHOH:GTP:RHOH effectors [plasma membrane] (Gallus gallus)
RHOH effectors [cytosol] (Gallus gallus)
PAK2 dimer [cytosol] (Gallus gallus)
PAK2 [cytosol] (Gallus gallus)
RHOQ GTPase cycle (Gallus gallus)
RHOQ binds effectors at the plasma membrane (Gallus gallus)
RHOQ effectors [cytosol] (Gallus gallus)
PAK2 dimer [cytosol] (Gallus gallus)
PAK2 [cytosol] (Gallus gallus)
RHOQ:GTP:RHOQ effectors [plasma membrane] (Gallus gallus)
RHOQ effectors [cytosol] (Gallus gallus)
PAK2 dimer [cytosol] (Gallus gallus)
PAK2 [cytosol] (Gallus gallus)
RHOU GTPase cycle (Gallus gallus)
RHOU binds effectors at the plasma membrane (Gallus gallus)
RHOU effectors [cytosol] (Gallus gallus)
PAK2 dimer [cytosol] (Gallus gallus)
PAK2 [cytosol] (Gallus gallus)
RHOU:GTP:RHOU effectors [plasma membrane] (Gallus gallus)
RHOU effectors [cytosol] (Gallus gallus)
PAK2 dimer [cytosol] (Gallus gallus)
PAK2 [cytosol] (Gallus gallus)
RHOV GTPase cycle (Gallus gallus)
RHOV binds effectors at the plasma membrane (Gallus gallus)
RHOV effectors [cytosol] (Gallus gallus)
PAK2 dimer [cytosol] (Gallus gallus)
PAK2 [cytosol] (Gallus gallus)
RHOV:GTP:RHOV effectors [plasma membrane] (Gallus gallus)
RHOV effectors [cytosol] (Gallus gallus)
PAK2 dimer [cytosol] (Gallus gallus)
PAK2 [cytosol] (Gallus gallus)
External Reference Information
External Reference
UniProt:E1BS97
Gene Names
PAK2
Reference Genes
BioGPS Gene:424860 PAK2
ENSEMBL:ENSGALG00000006426
ENSEMBL:ENSGALG00010024742.1 PAK2
KEGG Gene (Gallus gallus):424860 PAK2
Monarch:424860 PAK2
NCBI Gene:424860 PAK2
Reference Transcript
RefSeq:XM_422671.4 PAK2
RefSeq:XM_004936995.2 PAK2
Other Identifiers
424860
GO:0000166
GO:0003824
GO:0004672
GO:0004674
GO:0005524
GO:0005634
GO:0005737
GO:0005829
GO:0005911
GO:0006468
GO:0007010
GO:0012501
GO:0014069
GO:0016310
GO:0016740
GO:0019901
GO:0023052
GO:0030154
GO:0030296
GO:0031267
GO:0034330
GO:0034333
GO:0035556
GO:0036211
GO:0042802
GO:0043066
GO:0043226
GO:0043408
GO:0048856
GO:0050731
GO:0050770
GO:0051179
GO:0051493
GO:0051497
GO:0060996
GO:0070830
GO:0071407
GO:0098772
GO:0098978
GO:0140096
GO:0150105
GO:2001238
GT_A_87_P077026
GT_A_87_P126293
GT_A_87_P149223
GT_Sp_Chicken_CO764211_8607
Gga.7822.1.S1_at
GgaAffx.3992.1.S1_s_at
Participates
as a candidate of
PAK1/3, 2 [cytosol] (Gallus gallus)
as an output of
RAC1 and CDC42 activate PAK2 (Gallus gallus)
as a component of
CDC42:GTP,RAC1:GTP:PAK2 [plasma membrane] (Gallus gallus)
PAK2 dimer [cytosol] (Gallus gallus)
as a member of
PAK1,2,3 [cytosol] (Gallus gallus)
Other forms of this molecule
phospho-PAK2 [plasma membrane]
phospho-PAK2 [cytosol]
phospho-PAK2 [cytosol]
Inferred From
PAK2 [cytosol]
(Homo sapiens)
Cross References
RefSeq
XP_004937052.1
,
XP_422671.2
OpenTargets
ENSG00000180370
Ensembl
ENSGALP00010037162
,
ENSGALT00010060403
,
ENSGALG00010024742
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