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SMAD7 [cytosol]
Stable Identifier
R-GGA-173478
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
cytosol
Synonyms
SMAD7, A0A1D5PNY8
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Gallus gallus)
Post-translational protein modification (Gallus gallus)
Deubiquitination (Gallus gallus)
Ub-specific processing proteases (Gallus gallus)
USP15 deubiquitinates SMAD1,SMAD2,SMAD3, SMAD7:SMURF,KEAP1 (Gallus gallus)
USP15:SMAD1,SMAD2,SMAD3,KEAP1,SMAD7:SMURF2:TGFBR1 [cytosol] (Gallus gallus)
SMAD1,SMAD2,SMAD3,KEAP1,SMAD7:SMURF2:TGFBR1 [cytosol] (Gallus gallus)
SMAD7:SMURF2:TGFBR1 [plasma membrane] (Gallus gallus)
SMAD7:SMURF2 [cytosol] (Gallus gallus)
SMAD7 [cytosol] (Gallus gallus)
USP15:Ub-SMAD1,Ub-SMAD2,Ub-SMAD3,,Ub-KEAP1,SMAD7:SMURF2:Ub-TGFBR1 [cytosol] (Gallus gallus)
Ub-SMAD1,Ub-SMAD2,Ub-SMAD3,,Ub-KEAP1,SMAD7:SMURF2:Ub-TGFBR1 [cytosol] (Gallus gallus)
SMAD7:SMURF2:Ub-TGFBR1 [plasma membrane] (Gallus gallus)
SMAD7 [cytosol] (Gallus gallus)
Signal Transduction (Gallus gallus)
Signaling by TGFB family members (Gallus gallus)
Signaling by BMP (Gallus gallus)
I-Smad binds to type I receptor, preventing Smad1/5/8 from being activated (Gallus gallus)
BMP:p-BMPR:I-SMAD:SMURF [plasma membrane] (Gallus gallus)
I-SMAD:SMURF [cytosol] (Gallus gallus)
I-SMAD [cytosol] (Gallus gallus)
SMAD7 [cytosol] (Gallus gallus)
I-SMAD:SMURF [cytosol] (Gallus gallus)
I-SMAD [cytosol] (Gallus gallus)
SMAD7 [cytosol] (Gallus gallus)
I-Smad competes with Co-Smad for R-Smad1/5/8 (Gallus gallus)
I-SMAD [cytosol] (Gallus gallus)
SMAD7 [cytosol] (Gallus gallus)
I-SMAD:p-2S-SMAD1/5/8 [cytosol] (Gallus gallus)
I-SMAD [cytosol] (Gallus gallus)
SMAD7 [cytosol] (Gallus gallus)
I-Smad competes with R-Smad1/5/8 for type I receptor (Gallus gallus)
BMP2:BMP type II receptor:Phospho-BMP type I receptor:I-SMAD [plasma membrane] (Gallus gallus)
I-SMAD [cytosol] (Gallus gallus)
SMAD7 [cytosol] (Gallus gallus)
I-SMAD [cytosol] (Gallus gallus)
SMAD7 [cytosol] (Gallus gallus)
Signaling by TGF-beta Receptor Complex (Gallus gallus)
TGF-beta receptor signaling activates SMADs (Gallus gallus)
Downregulation of TGF-beta receptor signaling (Gallus gallus)
BAMBI interferes with the interaction of type I receptor with type II receptor (Gallus gallus)
SMAD7 [cytosol] (Gallus gallus)
TGFB1: TGFBR2: p-TGFBR1: BAMBI: SMAD7 [plasma membrane] (Gallus gallus)
SMAD7 [cytosol] (Gallus gallus)
Degradation of TGF-beta receptor complex (Gallus gallus)
TGFB1:TGFBR2:Ub-p-TGFBR1:Ub-SMAD7 [plasma membrane] (Gallus gallus)
TGFB1: p-TGFBR: I-SMAD7 [plasma membrane] (Gallus gallus)
SMAD7 [cytosol] (Gallus gallus)
I-SMAD competes with SMAD2/3 for type I receptor (TGFBR1) (Gallus gallus)
SMAD7 [cytosol] (Gallus gallus)
TGFB1: p-TGFBR: I-SMAD7 [plasma membrane] (Gallus gallus)
SMAD7 [cytosol] (Gallus gallus)
STRAP stabilizes interaction of activated TGF-beta receptor complex with SMAD7 (Gallus gallus)
SMAD7 [cytosol] (Gallus gallus)
TGFB1: p-TGFBR: STRAP: SMAD7 [plasma membrane] (Gallus gallus)
SMAD7 [cytosol] (Gallus gallus)
External Reference Information
External Reference
UniProt:A0A1D5PNY8
Gene Names
SMAD7
Reference Genes
BioGPS Gene:429683 SMAD7
ENSEMBL:ENSGALG00000037160
ENSEMBL:ENSGALG00010009910.1 SMAD7
Monarch:429683 SMAD7
NCBI Gene:429683 SMAD7
Reference Transcript
RefSeq:XM_427238.5 SMAD7
Other Identifiers
429683
GO:0005515
GO:0005634
GO:0005667
GO:0005737
GO:0005768
GO:0005769
GO:0006351
GO:0006355
GO:0006357
GO:0007179
GO:0009653
GO:0023052
GO:0030154
GO:0031410
GO:0043226
GO:0046872
GO:0048856
GO:0060395
GO:0070411
GO:0071144
GO:0098772
GO:0140416
GT_A_87_P012456
GT_A_87_P160403
Gga.19813.1.S1_at
GgaAffx.5663.1.S1_at
Participates
as a component of
SMAD7:SMURF2:Ub-TGFBR1 [plasma membrane] (Gallus gallus)
TGFB1: TGFBR2: p-TGFBR1: BAMBI: SMAD7 [plasma membrane] (Gallus gallus)
SMAD7:SMURF2 [cytosol] (Gallus gallus)
TGFB1: p-TGFBR: STRAP: SMAD7 [plasma membrane] (Gallus gallus)
TGFB1: p-TGFBR: I-SMAD7 [plasma membrane] (Gallus gallus)
as a member of
I-SMAD [cytosol] (Gallus gallus)
as an input of
BAMBI interferes with the interaction of type I receptor with type II receptor (Gallus gallus)
STRAP stabilizes interaction of activated TGF-beta receptor complex with SMAD7 (Gallus gallus)
I-SMAD competes with SMAD2/3 for type I receptor (TGFBR1) (Gallus gallus)
Other forms of this molecule
SMAD7 [nucleoplasm]
Inferred From
SMAD7 [cytosol]
(Homo sapiens)
Cross References
RefSeq
XP_427238.2
OpenTargets
ENSG00000101665
Ensembl
ENSGALT00010023630
,
ENSGALP00010013574
,
ENSGALG00010009910
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