Reactome | phospho-dos [cytosol]

phospho-dos [cytosol]

Stable Identifier

R-DME-912529

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

cytosol

Synonyms

p-Y-GAB2, Q9VZZ9

Locations in the PathwayBrowser

Expand all

Signal Transduction (Drosophila melanogaster)

- Signaling by Receptor Tyrosine Kinases (Drosophila melanogaster)
  - Signaling by Insulin receptor (Drosophila melanogaster)
    - Insulin receptor signalling cascade (Drosophila melanogaster)
      - IRS-mediated signalling (Drosophila melanogaster)
        
        PI3K Cascade (Drosophila melanogaster)
        
        PI3K-containing complexes phosphorylate PIP2 to PIP3 (Drosophila melanogaster)
        
        PI3K-containing complexes [cytosol] (Drosophila melanogaster)
        
        Active FLT3:GRB2:p-Y-GAB2:PIK3R1 [cytosol] (Drosophila melanogaster)
        
        Active FLT3:GRB2:p-Y-GAB2 [plasma membrane] (Drosophila melanogaster)
        
        phospho-dos [cytosol] (Drosophila melanogaster)
  - Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) (Drosophila melanogaster)
    - IGF1R signaling cascade (Drosophila melanogaster)
      - IRS-related events triggered by IGF1R (Drosophila melanogaster)
        
        IRS-mediated signalling (Drosophila melanogaster)
        
        PI3K Cascade (Drosophila melanogaster)
        
        PI3K-containing complexes phosphorylate PIP2 to PIP3 (Drosophila melanogaster)
        
        PI3K-containing complexes [cytosol] (Drosophila melanogaster)
        
        Active FLT3:GRB2:p-Y-GAB2:PIK3R1 [cytosol] (Drosophila melanogaster)
        
        Active FLT3:GRB2:p-Y-GAB2 [plasma membrane] (Drosophila melanogaster)
        
        phospho-dos [cytosol] (Drosophila melanogaster)

External Reference Information

External Reference

UniProt:Q9VZZ9

Gene Names

dos

Reference Genes

BioGPS Gene:38321 dos

CTD Gene:38321 dos

ENSEMBL:FBgn0016794

Flybase:FBgn0016794

KEGG Gene (Drosophila melanogaster):Dmel_CG1044 dos

Monarch:38321 dos

NCBI Gene:38321 dos

UCSC:Q9VZZ9 dos

Reference Transcript

Other Identifiers

141511_at

1640395_a_at

38321

GO:0005515

GO:0005737

GO:0005886

GO:0007165

GO:0007465

GO:0008293

GO:0008595

GO:0016020

GO:0023052

GO:0030154

GO:0035591

GO:0042169

GO:0042461

GO:0045500

GO:0046578

GO:0048856

GO:0060090

Participates

as a component of

Active FLT3:GRB2:p-Y-GAB2 [plasma membrane] (Drosophila melanogaster)

Other forms of this molecule

phospho-dos [cytosol]

dos [cytosol]

phospho-dos [cytosol]

dos [cytosol]

Inferred From

p-Y-GAB2 [cytosol] (Homo sapiens)

Modified Residues

Name

O4'-phospho-L-tyrosine at unknown position

PsiMod Name

O4'-phospho-L-tyrosine [MOD:00048]

PsiMod Definition

A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.

Cross References

RefSeq

NP_728757.1, NP_523890.2

Flybase

FBgn0016794

PRO

Q9VZZ9

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q08012	3	drk [cytosol] (R-DME-202367) drk [plasma membrane] (R-DME-202993) drk [cytosol] (R-DME-74686)	0.667	6

Cite Us!